Markers help to predict dementia with Lewy bodies

IF 28.2 1区医学 Q1 CLINICAL NEUROLOGY Nature Reviews Neurology Pub Date : 2025-01-17 DOI:10.1038/s41582-025-01058-x

Ian Fyfe

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标记物有助于预测路易体痴呆

一项新的研究表明，阿尔茨海默病（AD）病理学的生物标志物可以预测特发性快速眼动睡眠行为障碍（iRBD）患者路易体痴呆（DLB）的发展。我们测量了142名iRBD患者血液中淀粉样蛋白-β40 （Aβ40）、Aβ42和磷酸化tau-181 （pTau181）的水平。在发展为DLB的人群中，a - β40与a - β42的比例低于未发展为DLB的人群，而pTau181的水平高于未发展为DLB的人群。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature Reviews Neurology 医学-临床神经学

CiteScore

29.90

自引率

0.80%

发文量

138

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Neurology aims to be the premier source of reviews and commentaries for the scientific and clinical communities we serve. We want to provide an unparalleled service to authors, referees, and readers, and we work hard to maximize the usefulness and impact of each article. The journal publishes Research Highlights, Comments, News & Views, Reviews, Consensus Statements, and Perspectives relevant to researchers and clinicians working in the field of neurology. Our broad scope ensures that the work we publish reaches the widest possible audience. Our articles are authoritative, accessible, and enhanced with clearly understandable figures, tables, and other display items. This page gives more detail about the aims and scope of the journal.

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