Long-range inputome of prefrontal GABAergic interneurons in the Alzheimer's disease mouse

IF 13 1区 医学 Q1 CLINICAL NEUROLOGY Alzheimer's & Dementia Pub Date : 2025-01-17 DOI:10.1002/alz.14552
Miao Ren, Yuxiao Li, Tao Jiang, Bimin Liu, Xuhan Li, Xueyan Jia, Anan Li, Qingming Luo, Hui Gong, Xiangning Li
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Abstract

Alzheimer's disease (AD) is the most common neurodegenerative disease, characterized by damage to cortical circuits. However, the mechanisms underlying AD-associated changes in long-range circuits remain poorly understood.
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阿尔茨海默病小鼠前额叶gaba能中间神经元的远程输入
阿尔茨海默病(AD)是最常见的神经退行性疾病,其特征是皮层回路损伤。然而,ad相关的远程电路变化的机制仍然知之甚少。
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来源期刊
Alzheimer's & Dementia
Alzheimer's & Dementia 医学-临床神经学
CiteScore
14.50
自引率
5.00%
发文量
299
审稿时长
3 months
期刊介绍: Alzheimer's & Dementia is a peer-reviewed journal that aims to bridge knowledge gaps in dementia research by covering the entire spectrum, from basic science to clinical trials to social and behavioral investigations. It provides a platform for rapid communication of new findings and ideas, optimal translation of research into practical applications, increasing knowledge across diverse disciplines for early detection, diagnosis, and intervention, and identifying promising new research directions. In July 2008, Alzheimer's & Dementia was accepted for indexing by MEDLINE, recognizing its scientific merit and contribution to Alzheimer's research.
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