Hashing the message with cells

IF 12.9 1区 生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Nature chemical biology Pub Date : 2025-01-20 DOI:10.1038/s41589-024-01830-y
Jongmin Kim, Elisa Franco
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Abstract

The programming of multicellular processes for biological computation requires increasingly complex genetic circuit design. Through automated circuit design, it is now possible to systematically break down complex response functions into dozens of interconnected simplified logic circuits, each embeddable in distinct cellular strains.

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用单元格对消息进行散列
多细胞生物计算过程的编程要求越来越复杂的遗传电路设计。通过自动化电路设计,现在可以系统地将复杂的响应函数分解成数十个相互连接的简化逻辑电路,每个电路都可嵌入不同的细胞菌株中。
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来源期刊
Nature chemical biology
Nature chemical biology 生物-生化与分子生物学
CiteScore
23.90
自引率
1.40%
发文量
238
审稿时长
12 months
期刊介绍: Nature Chemical Biology stands as an esteemed international monthly journal, offering a prominent platform for the chemical biology community to showcase top-tier original research and commentary. Operating at the crossroads of chemistry, biology, and related disciplines, chemical biology utilizes scientific ideas and approaches to comprehend and manipulate biological systems with molecular precision. The journal embraces contributions from the growing community of chemical biologists, encompassing insights from chemists applying principles and tools to biological inquiries and biologists striving to comprehend and control molecular-level biological processes. We prioritize studies unveiling significant conceptual or practical advancements in areas where chemistry and biology intersect, emphasizing basic research, especially those reporting novel chemical or biological tools and offering profound molecular-level insights into underlying biological mechanisms. Nature Chemical Biology also welcomes manuscripts describing applied molecular studies at the chemistry-biology interface due to the broad utility of chemical biology approaches in manipulating or engineering biological systems. Irrespective of scientific focus, we actively seek submissions that creatively blend chemistry and biology, particularly those providing substantial conceptual or methodological breakthroughs with the potential to open innovative research avenues. The journal maintains a robust and impartial review process, emphasizing thorough chemical and biological characterization.
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