{"title":"Photonics of Bilirubin: A Biologically Important Molecule (Review)","authors":"A. S. Tatikolov, I. G. Panova","doi":"10.1134/S1990793124701173","DOIUrl":null,"url":null,"abstract":"<p>Bilirubin (BR), a bile pigment with photochemical activity, plays an important role in the body. The photonics (photophysics and photochemistry) of BR continues to attract scientific and practical interest from researchers to this day. This is due to the fact that its molecule is capable of ultrafast photoisomerization processes and also contains two interacting dipyrromethenone chromophores. Furthermore, the photochemical reactions of BR are used in the widespread phototherapy method of neonatal jaundice (neonatal hyperbilirubinemia (NHB)), carried out to reduce the level of BR in the body. This review briefly discusses the photonics of BR and its main photochemical reactions in the phototherapy of NHB.</p>","PeriodicalId":768,"journal":{"name":"Russian Journal of Physical Chemistry B","volume":"18 6","pages":"1473 - 1477"},"PeriodicalIF":1.4000,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Russian Journal of Physical Chemistry B","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1134/S1990793124701173","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PHYSICS, ATOMIC, MOLECULAR & CHEMICAL","Score":null,"Total":0}
引用次数: 0
Abstract
Bilirubin (BR), a bile pigment with photochemical activity, plays an important role in the body. The photonics (photophysics and photochemistry) of BR continues to attract scientific and practical interest from researchers to this day. This is due to the fact that its molecule is capable of ultrafast photoisomerization processes and also contains two interacting dipyrromethenone chromophores. Furthermore, the photochemical reactions of BR are used in the widespread phototherapy method of neonatal jaundice (neonatal hyperbilirubinemia (NHB)), carried out to reduce the level of BR in the body. This review briefly discusses the photonics of BR and its main photochemical reactions in the phototherapy of NHB.
期刊介绍：
Russian Journal of Physical Chemistry B: Focus on Physics is a journal that publishes studies in the following areas: elementary physical and chemical processes; structure of chemical compounds, reactivity, effect of external field and environment on chemical transformations; molecular dynamics and molecular organization; dynamics and kinetics of photoand radiation-induced processes; mechanism of chemical reactions in gas and condensed phases and at interfaces; chain and thermal processes of ignition, combustion and detonation in gases, two-phase and condensed systems; shock waves; new physical methods of examining chemical reactions; and biological processes in chemical physics.
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