Two-fluid flow of blood in a curved stenotic artery under pulsating condition

IF 1.8 4区 生物学 Q3 BIOPHYSICS Journal of Biological Physics Pub Date : 2025-01-22 DOI:10.1007/s10867-024-09668-0
Muhammad Shahzad Shabbir, Meriyem Hussain
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Abstract

The present article focuses on the analysis of the two-phase flow of blood via a stenosed artery under the influence of a pulsatile pressure gradient. The core and plasma regions of flow are modeled using the constitutive relations of Herschel-Bulkley and the Newtonian fluids, respectively. The problem is modeled in a cylindrical coordinate system. A modest stenosis assumption is used to simplify the non-dimensional governing equations of the flow issue. An explicit finite difference approach is used to solve the resultant nonlinear system of differential equations while accounting for the provided boundary conditions. After the necessary adjustments have been made to the crucial non-dimensional parameters, an analysis of the data behind the huge image, such as axial velocity, temperature field, concentration wall shear stress, flow rate, and flow impedance, is conducted. The current study shows that the curvature of blood vessels plays a significant role in influencing blood velocity. Specifically, a unit increase in the curvature radius results in a 24% rise in blood velocity.

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弯曲狭窄动脉在搏动状态下的双流体血流
本文着重分析了脉动压力梯度影响下血管狭窄的两相血流。流动的核心和等离子体区域分别使用赫歇尔-巴尔克利和牛顿流体的本构关系进行建模。该问题在柱坐标系中建模。采用适度狭窄假设来简化流动问题的无量纲控制方程。在考虑给定边界条件的情况下,采用显式有限差分法求解所得到的非线性微分方程组。在对关键的无量纲参数进行必要的调整后,对巨幅图像背后的数据进行分析,如轴向速度、温度场、浓壁剪应力、流速、流动阻抗等。目前的研究表明,血管的曲率对血流速度有重要的影响。具体来说,曲率半径每增加一个单位,血流速度就会增加24%。
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来源期刊
Journal of Biological Physics
Journal of Biological Physics 生物-生物物理
CiteScore
3.00
自引率
5.60%
发文量
20
审稿时长
>12 weeks
期刊介绍: Many physicists are turning their attention to domains that were not traditionally part of physics and are applying the sophisticated tools of theoretical, computational and experimental physics to investigate biological processes, systems and materials. The Journal of Biological Physics provides a medium where this growing community of scientists can publish its results and discuss its aims and methods. It welcomes papers which use the tools of physics in an innovative way to study biological problems, as well as research aimed at providing a better understanding of the physical principles underlying biological processes.
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