Eunice Man Ki Lo, Sisi Chen, Karen Hoi Ling Ng, Randolph Hung Leung Wong
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引用次数: 0
Abstract
Background and objective: Patients with thoracic aortic aneurysm and dissection (TAAD) are often asymptomatic but present acutely with life threatening complications that necessitate emergency intervention. Aortic diameter measurement using computed tomography (CT) is considered the gold standard for diagnosis, surgical planning, and monitoring. However, manual measurement can create challenges in clinical workflows due to its time-consuming, labour-intensive nature and susceptibility to human error. With advancements in artificial intelligence (AI), several models have emerged in recent years for automated aortic diameter measurement. This article aims to review the performance and clinical relevance of these models in relation to clinical workflows.
Methods: We performed literature searches in PubMed, Scopus, and Web of Science to identify relevant studies published between 2014 and 2024, with the focus on AI and deep learning aortic diameter measurements in screening and diagnosis of TAAD.
Key content and findings: Twenty-four studies were retrieved in the past ten years, highlighting a significant knowledge gap in the field of translational medicine. The discussion included an overview of AI-powered models for aortic diameter measurement, as well as current clinical guidelines and workflows.
Conclusions: This article provides a thorough overview of AI and deep learning models designed for automatic aortic diameter measurement in the screening and diagnosis of thoracic aortic aneurysms (TAAs). We emphasize not only the performance of these technologies but also their clinical significance in enabling timely interventions for high-risk patients. Looking ahead, we envision a future where AI and deep learning-powered automatic aortic diameter measurement models will streamline TAAD clinical management.
背景和目的:胸主动脉瘤和夹层(TAAD)患者通常无症状,但急性出现危及生命的并发症,需要紧急干预。使用计算机断层扫描(CT)测量主动脉直径被认为是诊断、手术计划和监测的金标准。然而,人工测量由于其耗时、劳动密集的性质和易受人为错误的影响,可能会给临床工作流程带来挑战。随着人工智能(AI)的发展,近年来出现了几种自动测量主动脉直径的模型。本文旨在回顾与临床工作流程相关的这些模型的性能和临床相关性。方法:我们在PubMed、Scopus和Web of Science中检索2014 - 2024年间发表的相关研究,重点关注人工智能和深度学习主动脉直径测量在TAAD筛查和诊断中的应用。主要内容和发现:在过去十年中检索了24项研究,突出了转化医学领域的重大知识差距。讨论内容包括人工智能主动脉直径测量模型的概述,以及当前的临床指南和工作流程。结论:本文对用于胸主动脉瘤(TAAs)筛查和诊断的主动脉直径自动测量的人工智能和深度学习模型进行了全面概述。我们不仅强调这些技术的性能,而且强调它们在对高危患者进行及时干预方面的临床意义。展望未来,人工智能和深度学习驱动的自动主动脉直径测量模型将简化TAAD的临床管理。
期刊介绍:
The Annals of Translational Medicine (Ann Transl Med; ATM; Print ISSN 2305-5839; Online ISSN 2305-5847) is an international, peer-reviewed Open Access journal featuring original and observational investigations in the broad fields of laboratory, clinical, and public health research, aiming to provide practical up-to-date information in significant research from all subspecialties of medicine and to broaden the readers’ vision and horizon from bench to bed and bed to bench. It is published quarterly (April 2013- Dec. 2013), monthly (Jan. 2014 - Feb. 2015), biweekly (March 2015-) and openly distributed worldwide. Annals of Translational Medicine is indexed in PubMed in Sept 2014 and in SCIE in 2018. Specific areas of interest include, but not limited to, multimodality therapy, epidemiology, biomarkers, imaging, biology, pathology, and technical advances related to medicine. Submissions describing preclinical research with potential for application to human disease, and studies describing research obtained from preliminary human experimentation with potential to further the understanding of biological mechanism underlying disease are encouraged. Also warmly welcome are studies describing public health research pertinent to clinic, disease diagnosis and prevention, or healthcare policy. With a focus on interdisciplinary academic cooperation, ATM aims to expedite the translation of scientific discovery into new or improved standards of management and health outcomes practice.