Personalized medicine: An alternative for cancer treatment.

Devendra Singh, Vinay Kumar Dhiman, Minakshi Pandey, Vivek Kumar Dhiman, Avinash Sharma, Himanshu Pandey, Sunil Kumar Verma, Rajeev Pandey
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Abstract

The incidence of cancer continues to increase worldwide, resulting in significant physical, emotional, and financial challenges for individuals, families, communities, and healthcare systems. Cancer is projected to be responsible for approximately 10 million deaths in 2020, accounting for one in six deaths globally. Prostate, colon, lung, and breast cancers are the most common types of cancer. In India, it is estimated that there will be around 2.7 million cancer patients by 2020. Personalized medicine has the potential to offer an alternative approach to cancer treatment. Precision medicine, often known as personalized medicine, is a new cancer treatment technique that focuses on tailoring medication to each patient's specific genetic, biochemical, and lifestyle factors. The goal is to optimize tumor response while minimizing therapy side effects, resulting in improved patient care and quality of life. Personalized medicine allows for the creation of focused medicines that address specific gene mutations by leveraging knowledge about a patient's cancer, including its genetic makeup. Ongoing research seeks to detect gene modifications in diverse cancer types, produce novel diagnostic tools, and develop treatments that particularly target these genetic changes. In recent years, personalized medicine has achieved major advances in the treatment of solid tumors, with the promise to improve treatment precision, reduce side effects, as well as enhance outcomes for patients in cancer therapy. This review aims to objectively evaluate the transformation of cancer treatment, emphasizing the shift towards a more precise methodology.

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个性化医疗:癌症治疗的另一种选择。
全球癌症发病率持续上升,给个人、家庭、社区和卫生保健系统带来了重大的身体、情感和经济挑战。预计到2020年,癌症将导致约1000万人死亡,占全球死亡人数的六分之一。前列腺癌、结肠癌、肺癌和乳腺癌是最常见的癌症类型。据估计,到2020年,印度将有大约270万癌症患者。个性化医疗有可能为癌症治疗提供另一种方法。精准医疗,通常被称为个性化医疗,是一种新的癌症治疗技术,专注于根据每个患者特定的基因、生化和生活方式因素定制药物。目标是优化肿瘤反应,同时尽量减少治疗副作用,从而改善患者的护理和生活质量。个性化医疗允许通过利用对患者癌症的了解,包括其基因组成,来创造针对特定基因突变的针对性药物。正在进行的研究旨在检测不同癌症类型的基因修饰,产生新的诊断工具,并开发特别针对这些基因变化的治疗方法。近年来,个性化医疗在实体瘤治疗方面取得了重大进展,有望提高治疗精度,减少副作用,并提高癌症治疗患者的预后。这篇综述旨在客观地评价癌症治疗的转变,强调向更精确的方法的转变。
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来源期刊
CiteScore
4.30
自引率
0.00%
发文量
148
审稿时长
56 days
期刊介绍: Cancer Treatment and Research Communications is an international peer-reviewed publication dedicated to providing comprehensive basic, translational, and clinical oncology research. The journal is devoted to articles on detection, diagnosis, prevention, policy, and treatment of cancer and provides a global forum for the nurturing and development of future generations of oncology scientists. Cancer Treatment and Research Communications publishes comprehensive reviews and original studies describing various aspects of basic through clinical research of all tumor types. The journal also accepts clinical studies in oncology, with an emphasis on prospective early phase clinical trials. Specific areas of interest include basic, translational, and clinical research and mechanistic approaches; cancer biology; molecular carcinogenesis; genetics and genomics; stem cell and developmental biology; immunology; molecular and cellular oncology; systems biology; drug sensitivity and resistance; gene and antisense therapy; pathology, markers, and prognostic indicators; chemoprevention strategies; multimodality therapy; cancer policy; and integration of various approaches. Our mission is to be the premier source of relevant information through promoting excellence in research and facilitating the timely translation of that science to health care and clinical practice.
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