Experimental Evidence of the Benefits of Acupuncture/Electroacupuncture for Acute Lung Injury/ Acute Respiratory Distress Syndrome: A Literature Review of Rodent Studies.

IF 2.2 4区 医学 Q3 MEDICINE, RESEARCH & EXPERIMENTAL Current molecular medicine Pub Date : 2025-01-14 DOI:10.2174/0115665240334516241123130753
Lin Zeng, Jiangtian Yan
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Abstract

Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) encompass various etiologies and are distinguished by the onset of acute pulmonary inflammation and heightened permeability of the pulmonary vasculature, often leading to substantial morbidity and frequent mortality. There is a scarcity of viable approaches for treating effectively. In recent decades, acupuncture has been proven to be antiinflammatory. This review aims to provide a comprehensive summary of the previously documented mechanisms underlying the beneficial effects of acupuncture in ALI/ARDS, including inhibiting excessive oxidative stress, alleviating pulmonary inflammatory response, suppressing programmed cell death, and protecting the alveolar-capillary membrane. Collectively, these findings indicate that acupuncture yields therapeutic benefits for ALI/ARDS.

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针刺/电针治疗急性肺损伤/急性呼吸窘迫综合征的实验证据:啮齿动物研究的文献综述。
急性肺损伤(ALI)和急性呼吸窘迫综合征(ARDS)包括多种病因,其特点是急性肺部炎症和肺血管通透性增高,通常导致大量发病率和死亡率。目前缺乏有效治疗的可行方法。近几十年来,针灸已被证明具有抗炎作用。本文旨在全面总结针刺治疗ALI/ARDS的机制,包括抑制过度氧化应激、减轻肺部炎症反应、抑制程序性细胞死亡和保护肺泡毛细血管膜。总的来说,这些发现表明针灸对急性呼吸窘迫综合征/急性呼吸窘迫综合征有治疗作用。
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来源期刊
Current molecular medicine
Current molecular medicine 医学-医学:研究与实验
CiteScore
5.00
自引率
4.00%
发文量
141
审稿时长
4-8 weeks
期刊介绍: Current Molecular Medicine is an interdisciplinary journal focused on providing the readership with current and comprehensive reviews/ mini-reviews, original research articles, short communications/letters and drug clinical trial studies on fundamental molecular mechanisms of disease pathogenesis, the development of molecular-diagnosis and/or novel approaches to rational treatment. The reviews should be of significant interest to basic researchers and clinical investigators in molecular medicine. Periodically the journal invites guest editors to devote an issue on a basic research area that shows promise to advance our understanding of the molecular mechanism(s) of a disease or has potential for clinical applications.
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