A case of autoimmune haemolytic anaemia associated with mediastinal teratoma.

IF 0.7 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Indian Journal of Thoracic and Cardiovascular Surgery Pub Date : 2025-02-01 Epub Date: 2024-06-19 DOI:10.1007/s12055-024-01773-y

Muralidhara Yadiyal Baregundi, Prajjwal Bansal, Bhushan Chandrahasa Shetty

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Abstract

Autoimmune hemolytic anemia (AIHA) secondary to mediastinal teratoma is a very rare clinical entity. They can be primary or secondary to any infections, malignancy, etc. Yet at times, there could be a delay in the diagnosis. Here we present a rare presentation of mediastinal teratoma and probably this is the first from India, based on our literature review using PubMed and Scopus as search engines with MeSH (Medical Subject Headings) words "mediastinal teratoma AND India AND hemolytic anemia." A 26-year-old male with cough and effort intolerance was diagnosed with AIHA which was triggered by a mediastinal teratoma. He had difficulty in preprocedural blood transfusion due to incompatibility which needed high-dose methylprednisolone to suppress the immune system. Due to prior usage of pulse steroids, we had the challenge of ruling out hematological malignancy, which was done by bone marrow examination and positron emission tomography (PET) scan of the whole body. AIHA resolved completely with open thoracotomy and excision of the tumor.

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纵隔畸胎瘤合并自身免疫性溶血性贫血1例。

摘要继发于纵隔畸胎瘤的自身免疫性溶血性贫血是一种非常罕见的临床疾病。它们可以是原发性或继发于任何感染、恶性肿瘤等。然而有时，诊断可能会延迟。在这里，我们报告了一例罕见的纵隔畸胎瘤，这可能是第一例来自印度的病例，基于我们使用PubMed和Scopus作为搜索引擎，搜索MeSH（医学主题标题）词“纵隔畸胎瘤、印度和溶血性贫血”的文献综述。一位26岁男性，咳嗽和努力不耐受被诊断为AIHA，这是由纵隔畸胎瘤引发的。手术前输血困难，需大剂量甲基强的松龙抑制免疫系统。由于先前使用脉冲类固醇，我们有排除血液系统恶性肿瘤的挑战，这是通过骨髓检查和全身正电子发射断层扫描（PET）完成的。经开胸切除肿瘤，AIHA完全消失。

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来源期刊

Indian Journal of Thoracic and Cardiovascular Surgery CARDIAC & CARDIOVASCULAR SYSTEMS-

CiteScore

1.20

自引率

14.30%

发文量

141

期刊介绍： The primary aim of the Indian Journal of Thoracic and Cardiovascular Surgery is education. The journal aims to dissipate current clinical practices and developments in the area of cardiovascular and thoracic surgery. This includes information on cardiovascular epidemiology, aetiopathogenesis, clinical manifestation etc. The journal accepts manuscripts from cardiovascular anaesthesia, cardiothoracic and vascular nursing and technology development and new/innovative products.The journal is the official publication of the Indian Association of Cardiovascular and Thoracic Surgeons which has a membership of over 1000 at present.DescriptionThe journal is the official organ of the Indian Association of Cardiovascular-Thoracic Surgeons. It was started in 1982 by Dr. Solomon Victor and ws being published twice a year up to 1996. From 2000 the editorial office moved to Delhi. From 2001 the journal was extended to quarterly and subsequently four issues annually have been printed out at time and regularly without fail. The journal receives manuscripts from members and non-members and cardiovascular surgeons. The manuscripts are peer reviewed by at least two or sometimes three or four reviewers who are on the panel. The manuscript process is now completely online. Funding the journal comes partially from the organization and from revenue generated by subscription and advertisement.