Assessing the safety and effectiveness of endoscopic ultrasound for pediatric hepato-pancreatico-biliary disorders: a systematic review.

IF 2.1 3区医学 Q2 PEDIATRICS Pediatric Radiology Pub Date : 2025-02-01 Epub Date: 2025-01-17 DOI:10.1007/s00247-024-06159-1

Omar Alomari, Khaled A Abualkhair, Khaled Saad, Sara Magdy, Janna A Omran, Mahmoud M AlSanafini, Loay A Hassan, Omar Y ElBasatiny, Djihane Machane, Marwan Abdulrahim, Hadeer G Abo-Elmaged, Mohamed Elshaieb, Mohamed Shawky Elfarargy, Amira Elhoufey, Hamad Ghaleb Dailah, Aya H Sayed, Alaa Ismail, Bassel Walid, Mahmoud Hashemy, Ahmed M Afifi, Anas Elgenidy

{"title":"Assessing the safety and effectiveness of endoscopic ultrasound for pediatric hepato-pancreatico-biliary disorders: a systematic review.","authors":"Omar Alomari, Khaled A Abualkhair, Khaled Saad, Sara Magdy, Janna A Omran, Mahmoud M AlSanafini, Loay A Hassan, Omar Y ElBasatiny, Djihane Machane, Marwan Abdulrahim, Hadeer G Abo-Elmaged, Mohamed Elshaieb, Mohamed Shawky Elfarargy, Amira Elhoufey, Hamad Ghaleb Dailah, Aya H Sayed, Alaa Ismail, Bassel Walid, Mahmoud Hashemy, Ahmed M Afifi, Anas Elgenidy","doi":"10.1007/s00247-024-06159-1","DOIUrl":null,"url":null,"abstract":"Background: Endoscopic ultrasound (US) has been established as a safe diagnostic tool for adults, but its use in children remains underexplored. The rising prevalence of pediatric hepato-pancreato-biliary disorders requires a closer examination of its utility. In this systematic review, we aimed to evaluate the efficacy, safety, and clinical impact of endoscopic US in the pediatric population, concentrating on its diagnostic accuracy and therapeutic applications.Methods: All related clinical studies were identified by searching the Web of Science databases, PubMed (MEDLINE), Scopus, Cochrane, and Embase. Data were extracted from relevant studies using a pre-planned Excel sheet.Results: Twenty-eight studies demonstrated that endoscopic US in children is safe, technically successful, and clinically impactful, offering valuable diagnostic and interventional competencies. Endoscopic US was frequently used for microlithiasis, choledocholithiasis, and pancreaticobiliary anomalies. It reliably outperformed other imaging modalities, effectively reducing the need for more invasive procedures. Endoscopic US had a remarkable clinical impact, with diverse diagnostic yields, highlighting its role in diagnosing and treating children with hepato-pancreato-biliary disorders. The safety profile of endoscopic US in children was excellent, with nominal reported complications.Conclusion: Our comprehensive review underlines the promising application of endoscopic US in pediatric hepato-pancreato-biliary diseases. The endoscopic US demonstrates its diagnostic accuracy and therapeutic potential in children, offering a non-invasive, safe, and efficient approach. As we move forward, addressing the identified limitations and expanding the pediatric-specific research on endoscopic US will enhance our ability to provide precise and patient-centered care in managing pediatric hepato-pancreato-biliary disorders.","PeriodicalId":19755,"journal":{"name":"Pediatric Radiology","volume":" ","pages":"215-225"},"PeriodicalIF":2.1000,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pediatric Radiology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00247-024-06159-1","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/17 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"PEDIATRICS","Score":null,"Total":0}

引用次数: 0

Abstract

Background: Endoscopic ultrasound (US) has been established as a safe diagnostic tool for adults, but its use in children remains underexplored. The rising prevalence of pediatric hepato-pancreato-biliary disorders requires a closer examination of its utility. In this systematic review, we aimed to evaluate the efficacy, safety, and clinical impact of endoscopic US in the pediatric population, concentrating on its diagnostic accuracy and therapeutic applications.

Methods: All related clinical studies were identified by searching the Web of Science databases, PubMed (MEDLINE), Scopus, Cochrane, and Embase. Data were extracted from relevant studies using a pre-planned Excel sheet.

Results: Twenty-eight studies demonstrated that endoscopic US in children is safe, technically successful, and clinically impactful, offering valuable diagnostic and interventional competencies. Endoscopic US was frequently used for microlithiasis, choledocholithiasis, and pancreaticobiliary anomalies. It reliably outperformed other imaging modalities, effectively reducing the need for more invasive procedures. Endoscopic US had a remarkable clinical impact, with diverse diagnostic yields, highlighting its role in diagnosing and treating children with hepato-pancreato-biliary disorders. The safety profile of endoscopic US in children was excellent, with nominal reported complications.

Conclusion: Our comprehensive review underlines the promising application of endoscopic US in pediatric hepato-pancreato-biliary diseases. The endoscopic US demonstrates its diagnostic accuracy and therapeutic potential in children, offering a non-invasive, safe, and efficient approach. As we move forward, addressing the identified limitations and expanding the pediatric-specific research on endoscopic US will enhance our ability to provide precise and patient-centered care in managing pediatric hepato-pancreato-biliary disorders.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

评估内镜超声治疗小儿肝胆胰疾病的安全性和有效性：一项系统综述。

背景：内镜超声（US）已被确定为一种安全的成人诊断工具，但其在儿童中的应用仍未得到充分探索。儿科肝-胰-胆疾病患病率的上升需要对其效用进行更密切的检查。在本系统综述中，我们旨在评估内镜下US在儿科人群中的有效性、安全性和临床影响，重点关注其诊断准确性和治疗应用。方法：通过检索Web of Science数据库、PubMed （MEDLINE）、Scopus、Cochrane和Embase对所有相关临床研究进行鉴定。使用预先规划的Excel表格从相关研究中提取数据。结果：28项研究表明，儿童内镜下超声是安全的，技术上是成功的，临床有效的，提供了有价值的诊断和介入能力。内镜下超声检查常用于小结石、胆总管结石和胰胆管异常。它可靠地优于其他成像方式，有效地减少了对更多侵入性手术的需要。内镜下US具有显著的临床影响，诊断结果多样，突出了其在诊断和治疗儿童肝胆胰疾病中的作用。内镜下US在儿童中的安全性非常好，报道的并发症很少。结论：我们的综合综述强调了内镜下超声在小儿肝-胰-胆疾病中的应用前景。内镜下超声显示了其在儿童中的诊断准确性和治疗潜力，提供了一种非侵入性、安全和有效的方法。随着我们的进展，解决已确定的局限性并扩大内镜下US的儿科特异性研究将增强我们在管理儿科肝-胰-胆疾病方面提供精确和以患者为中心的护理的能力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Pediatric Radiology 医学-核医学

CiteScore

4.40

自引率

17.40%

发文量

300

审稿时长

3-6 weeks

期刊介绍： Official Journal of the European Society of Pediatric Radiology, the Society for Pediatric Radiology and the Asian and Oceanic Society for Pediatric Radiology Pediatric Radiology informs its readers of new findings and progress in all areas of pediatric imaging and in related fields. This is achieved by a blend of original papers, complemented by reviews that set out the present state of knowledge in a particular area of the specialty or summarize specific topics in which discussion has led to clear conclusions. Advances in technology, methodology, apparatus and auxiliary equipment are presented, and modifications of standard techniques are described. Manuscripts submitted for publication must contain a statement to the effect that all human studies have been reviewed by the appropriate ethics committee and have therefore been performed in accordance with the ethical standards laid down in an appropriate version of the 1964 Declaration of Helsinki. It should also be stated clearly in the text that all persons gave their informed consent prior to their inclusion in the study. Details that might disclose the identity of the subjects under study should be omitted.