{"title":"Effect of electronic cigarette atomising power and flavour on aerosol size-segregated metal concentration and inhalation risk.","authors":"Jinho Lee, Masoud Afshar, Wei-Chung Su, Inkyu Han","doi":"10.1136/tc-2024-058915","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Although numerous studies have estimated the inhalation dose of metals emitted from electronic cigarettes (e-cigs), the impact of factors including aerosol size and the atomising power of e-cig aerosols on estimating the inhalation dose of metals remains underexplored. A comprehensive understanding of these determinants is essential to assess the health risks associated with inhaling e-cig aerosols, which may contain potentially harmful metals.</p><p><strong>Objectives: </strong>The aim of this study is to elucidate the mass and inhalation doses of potentially harmful metals in e-cig aerosols by different particle size and their association with the various atomising powers of e-cig devices and flavours.</p><p><strong>Methods: </strong>Size-segregated e-cig aerosols were generated and collected in a exposure chamber, using an 11-stage cascade impactor for the analyses of aerosol mass and metals. The metal deposition dose in the human respiratory tract was calculated using a mathematical respiratory deposition estimation model and metal mass concentration by the size of aerosols.</p><p><strong>Results: </strong>In this study, the results showed that neither an increase in atomising power (from 5 to 20 W) nor e-cig flavours resulted in a significant increase in a metal deposition in the respiratory tracts. Although the factors did not significantly affect the calculated respiratory deposition of harmful metals under typical e-cig usage assumption, the estimated hazard index exceeded 1.0.</p><p><strong>Conclusion: </strong>The calculated health risks suggest substantial risks of inhalation of metal aerosols from e-cig use.</p>","PeriodicalId":23145,"journal":{"name":"Tobacco Control","volume":" ","pages":""},"PeriodicalIF":4.7000,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12260031/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Tobacco Control","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1136/tc-2024-058915","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
引用次数: 0
Abstract
Introduction: Although numerous studies have estimated the inhalation dose of metals emitted from electronic cigarettes (e-cigs), the impact of factors including aerosol size and the atomising power of e-cig aerosols on estimating the inhalation dose of metals remains underexplored. A comprehensive understanding of these determinants is essential to assess the health risks associated with inhaling e-cig aerosols, which may contain potentially harmful metals.
Objectives: The aim of this study is to elucidate the mass and inhalation doses of potentially harmful metals in e-cig aerosols by different particle size and their association with the various atomising powers of e-cig devices and flavours.
Methods: Size-segregated e-cig aerosols were generated and collected in a exposure chamber, using an 11-stage cascade impactor for the analyses of aerosol mass and metals. The metal deposition dose in the human respiratory tract was calculated using a mathematical respiratory deposition estimation model and metal mass concentration by the size of aerosols.
Results: In this study, the results showed that neither an increase in atomising power (from 5 to 20 W) nor e-cig flavours resulted in a significant increase in a metal deposition in the respiratory tracts. Although the factors did not significantly affect the calculated respiratory deposition of harmful metals under typical e-cig usage assumption, the estimated hazard index exceeded 1.0.
Conclusion: The calculated health risks suggest substantial risks of inhalation of metal aerosols from e-cig use.
期刊介绍：
Tobacco Control is an international peer-reviewed journal covering the nature and consequences of tobacco use worldwide; tobacco''s effects on population health, the economy, the environment, and society; efforts to prevent and control the global tobacco epidemic through population-level education and policy changes; the ethical dimensions of tobacco control policies; and the activities of the tobacco industry and its allies.
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