Caffeine and nicotine acutely inhibit flow-mediated vasodilation, but not both are necessarily harmful in the long term.

IF 2.1 4区 医学 Q3 PERIPHERAL VASCULAR DISEASE Vasa-european Journal of Vascular Medicine Pub Date : 2025-03-01 Epub Date: 2025-01-20 DOI:10.1024/0301-1526/a001167
Martin Storck, Knut Kröger, Christos Rammos
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Abstract

Today, flow-mediated dilation (FMD) is a standardized test for the non-invasive assessment of vascular endothelial function in humans. The test is often used to assess the influence of various living conditions on the vascular system. Many factors have a short-term effect on FMD and reduce it. However, not every short-term FMD-reducing effect also signals long-term vascular damage with repeated exposure. The comparison between coffee consumption and smoking will be used to discuss that although both stimulants lead to comparable acute changes in vascular function, they differ in their long-term effects on the vascular system. Therefore, acute FMD effects cannot always be equated with long-term damaging effects.

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咖啡因和尼古丁会严重抑制血流介导的血管舒张,但并非两者都是长期有害的。
今天,血流介导扩张(FMD)是一种非侵入性评估人类血管内皮功能的标准化测试。该试验常用于评估各种生活条件对血管系统的影响。许多因素对口蹄疫有短期影响,并能减少口蹄疫。然而,并不是每一个短期的fmd减少效果也表明长期的血管损伤与反复接触。喝咖啡和吸烟之间的比较将被用来讨论,尽管这两种兴奋剂都会导致血管功能的类似急性变化,但它们对血管系统的长期影响不同。因此,口蹄疫的急性影响不能总是等同于长期的破坏性影响。
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来源期刊
CiteScore
3.90
自引率
11.10%
发文量
61
审稿时长
1 months
期刊介绍: Vasa is the European journal of vascular medicine. It is the official organ of the German, Swiss, and Slovenian Societies of Angiology. The journal publishes original research articles, case reports and reviews on vascular biology, epidemiology, prevention, diagnosis, medical treatment and interventions for diseases of the arterial circulation, in the field of phlebology and lymphology including the microcirculation, except the cardiac circulation. Vasa combines basic science with clinical medicine making it relevant to all physicians interested in the whole vascular field.
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