The Burden of Diabetes in the Southeastern Coastal Region of China From 1990 to 2019 and Projections for 2030: A Systematic Analysis of the 2019 Global Burden of Disease Study

IF 4.6 2区 医学 Q1 ENDOCRINOLOGY & METABOLISM Diabetes/Metabolism Research and Reviews Pub Date : 2025-01-20 DOI:10.1002/dmrr.70031
Yating Ding, Xiuli Cai, Yangjiang Ou, Dong Liang, Qing Guan, Wenling Zhong, Xiuquan Lin
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Abstract

Aim

This study examined the diabetes burden in Fujian Province, China, from 1990 to 2019, comparing it with China and global levels to inform policymakers.

Materials and Methods

We used data from GBD 2019 to analyse diabetes prevalence, death, and disability-adjusted life-years (DALYs). We assessed the average annual percentage change (AAPC) and estimated the impact of 17 risk factors. An age-period-cohort model evaluated age, period, and cohort effects on diabetes metrics. Bayesian models forecasted prevalence and DALYs for 2020–2030, with frontier analysis linking DALYs to per capita GDP.

Results

In 2019, Fujian Province had approximately 2,359,179 diabetes cases with a prevalence rate of 4423.82 (95% UI 4004.12–4864.55) per 100,000 and an age-standardised DALYs of 475.00 (375.63–589.49) per 100,000, both lower than China and global averages. From 1990 to 2019, Fujian Province's age-standardised mortality rate remained higher than the China average, but the gap narrowed compared with 1990. Elderly males showed a pronounced increase in mortality. The period effect indicated a turning point during 2005–2009. DALYs increased among men and decreased among women over cohorts. By 2030, the DALYs rate is projected to decrease by 6.59%. Frontier analysis showed that compared with the same economic level, the effective difference in diabetes disease burden in Fujian Province was small, but there was room for improvement.

Conclusion

From 1990 to 2019, Fujian Province's age-standardised diabetes prevalence slightly increased, while mortality and DALYs declined. Significant gender and age disparities existed, highlighting the need for targeted strategies for elderly males. Fujian Province's success in diabetes management can provide a model for other regions.

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1990 - 2019年中国东南沿海地区糖尿病负担及2030年预测——对2019年全球疾病负担研究的系统分析
目的:本研究调查了1990年至2019年中国福建省的糖尿病负担,将其与中国和全球水平进行比较,为政策制定者提供信息。材料和方法:我们使用GBD 2019的数据来分析糖尿病患病率、死亡率和残疾调整生命年(DALYs)。我们评估了平均年百分比变化(AAPC),并估计了17个危险因素的影响。年龄-时期-队列模型评估年龄、时期和队列对糖尿病指标的影响。贝叶斯模型预测了2020-2030年的患病率和DALYs,前沿分析将DALYs与人均GDP联系起来。结果:2019年福建省糖尿病患者约2,359,179例,患病率为4423.82 (95% UI为4004.12-4864.55)/ 10万,年龄标准化DALYs为475.00(375.63-589.49)/ 10万,均低于中国和全球平均水平。1990年至2019年,福建省年龄标准化死亡率仍高于全国平均水平,但与1990年相比差距缩小。老年男性的死亡率明显上升。期间效应表明2005-2009年是一个转折点。在队列中,男性DALYs增加,女性DALYs减少。到2030年,DALYs比率预计将下降6.59%。前沿分析显示,与同等经济水平相比,福建省糖尿病疾病负担的有效差异较小,但仍有改善的空间。结论:1990 - 2019年,福建省年龄标准化糖尿病患病率略有上升,死亡率和DALYs下降。存在着显著的性别和年龄差异,突出表明需要为老年男性制定有针对性的战略。福建省在糖尿病管理方面的成功可以为其他地区提供借鉴。
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来源期刊
Diabetes/Metabolism Research and Reviews
Diabetes/Metabolism Research and Reviews 医学-内分泌学与代谢
CiteScore
17.20
自引率
2.50%
发文量
84
审稿时长
4-8 weeks
期刊介绍: Diabetes/Metabolism Research and Reviews is a premier endocrinology and metabolism journal esteemed by clinicians and researchers alike. Encompassing a wide spectrum of topics including diabetes, endocrinology, metabolism, and obesity, the journal eagerly accepts submissions ranging from clinical studies to basic and translational research, as well as reviews exploring historical progress, controversial issues, and prominent opinions in the field. Join us in advancing knowledge and understanding in the realm of diabetes and metabolism.
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