Expression of Concern: HSP27 Favors Ubiquitination and Proteasomal Degradation of p27Kip1 and Helps S-Phase Re-Entry in Stressed Cells

Abstract

Expression of Concern: A. Parcellier, M. Brunet, E. Schmitt, E. Col, C. Didelot, A. Hammann, K. Nakayama, K. I. Nakayama, S. Khochbin, E. Solary, and C. Garrido, “HSP27 Favors Ubiquitination and Proteasomal Degradation of p27^Kip1 and Helps S-Phase Re-Entry in Stressed Cells,” The FASEB Journal 20, no. 8 (2006): 1179–1181, https://doi.org/10.1096/fj.05-4184fje.

This Expression of Concern is for the above article, published online on April 26, 2006 in Wiley Online Library (wileyonlinelibrary.com), and has been published by agreement between the journal Editor-in-Chief, Loren E. Wold; the Federation of American Societies for Experimental Biology; and Wiley Periodicals LLC. This Expression of Concern has been published due to concerns raised by a third party regarding highly similar image sections within Figures 1A, D, E, F, and H, Figures 5A and B, Figure 7C and Figure 10A; a potential duplication between Figure 1A and Figure 10A; and unacknowledged splicings within Figure 2B, and Figures 3A and B. The authors were informed about the concerns, and they were able to provide a satisfactory explanation and partial raw data to the concerns regarding Figures 1A, 2B, 3A, 3B, and 1D. However, without an adequate explanation of the anomaly in the rest of the figures and in the absence of the original raw data, the journal team could not verify the authenticity of these figures and could not exclude that these concerns affect the related conclusions of the article. Therefore, the journal has decided to issue an Expression of Concern to inform and alert the readers.