MULTIMODAL IMAGING FINDINGS OF THE FELLOW EYE IN STELLATE NONHEREDITARY IDIOPATHIC FOVEOMACULAR RETINOSCHISIS.

Abstract

Purpose: This study examines the multimodal imaging findings in two cases of unilateral stellate nonhereditary idiopathic foveomacular retinoschisis, including detailed findings from the unaffected fellow eye.

Methods: Macular spectral domain optical coherence tomography and 3 × 3 mm optical coherence tomography angiography, microperimetry, and full-field electroretinography for both the affected and the fellow eye were reviewed.

Results: The multimodal imaging findings were consistent across the two cases (71-year-old woman and 60-year-old woman). Optical coherence tomography imaging of the affected eyes revealed cystoid spaces between the outer nuclear layer and the outer plexiform layer, with the vascular network remaining intact, indicating no alterations in vessel flow. Microperimetry showed slightly lower pointwise sensitivity in both eyes compared with a normative database.

Conclusion: Although stellate nonhereditary idiopathic foveomacular retinoschisis typically presents as a unilateral condition, our findings suggest that patients may have an inherent structural predisposition to macular schisis, resulting in subtle functional impairments. We hypothesize that the structural damage may involve the macular Muller cells. These observations highlight the importance of further studies to understand stellate nonhereditary idiopathic foveomacular retinoschisis's pathophysiology and inform therapeutic approaches.