Does Alexithymia Predict the Psychiatric Comorbidity Among Healthy Carriers of Hepatitis B?

IF 1.3 Q3 PSYCHIATRY Alpha psychiatry Pub Date : 2024-11-01 DOI:10.5152/alphapsychiatry.2024.21300
Nermin Gündüz, Özge Timur, Doğan Nasır Binici, Erkal Erzincan, Ahmet Yosmaoğlu
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Abstract

Objective: The psychiatric disorders among healthy carriers of hepatitis B (HBsAg), who have no severe physical disability or any medical treatment, have clinical importance. We aimed to research the comorbid psychiatric disorders and alexithymia and to identify whether alexithymia and accompanying somatic symptoms predict the presence of psychiatric diagnoses or not among HBsAg carriers.

Methods eighty-nine: healthy carriers of Hepatitis B patients and nınety-three healthy individuals were included to study. Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders (Fourth Edition) (DSM-IV) (SCID-I), Hamilton Depression Rating Scale (HAM-D), Hamilton Anxiety Rating Scale (HAM-A), and Toronto Alexithymia Scale (TAS) were applied.

Results: When the distribution of SCID I psychiatric diagnoses among healthy HBsAg carriers examined, majority of the patients (n = 53, 59.6%) had any psychiatric diagnosis. The logistic regression model evaluating whether number of somatic symptoms and alexithymia predict the psychiatric diagnosis, we observed that number of somatic symptoms predicted the presence of psychiatric diagnosis (odds ratio = 2.762, P < .001).

Conclusion: Our findings revealed that alexithymia may potentiate the occurrence of psychiatric disorders in such patients and that it requires more consideration. So, our results suggest that HBsAg carriers need multidisciplinary evaluation including hepatology, infection clinics and psychiatric liaison.

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述情障碍能预测健康乙型肝炎携带者的精神共病吗?
目的:健康乙型肝炎(HBsAg)携带者未发生严重身体残疾或未接受任何药物治疗的精神障碍具有重要的临床意义。我们的目的是研究精神疾病和述情障碍的共病,并确定述情障碍和伴随的躯体症状是否预测HBsAg携带者中精神诊断的存在。方法选取89例健康乙肝病毒携带者和nınety-three健康人作为研究对象。采用《精神障碍诊断与统计手册(第四版)》(DSM-IV) (SCID-I)、汉密尔顿抑郁评定量表(HAM-D)、汉密尔顿焦虑评定量表(HAM-A)和多伦多述情障碍量表(TAS)进行结构化临床访谈。结果:在检查健康HBsAg携带者中SCID I精神诊断分布时,大多数患者(n = 53, 59.6%)有精神诊断。采用logistic回归模型评价躯体症状数量和述情障碍是否能预测精神诊断,我们观察到躯体症状数量能预测精神诊断的存在(优势比= 2.762,P < 0.001)。结论:我们的研究结果表明,述情障碍可能会加剧这类患者精神障碍的发生,需要更多的考虑。因此,我们的研究结果表明,HBsAg携带者需要多学科评估,包括肝病学,感染临床和精神病学联络。
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