Passive Heat Therapy for Cardiovascular Disease: Current Evidence and Future Directions.

Saniya Rodrigues, Fergus O'Connor, N Morris, Georgia Chaseling, Surendran Sabapathy, Aaron Bach
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Abstract

Passive heat therapy is gaining popularity as an intervention to promote cardiovascular, physiological, and to a lesser degree, thermoregulatory, adaptations in patients with cardiovascular disease. Despite this, the efficacy of heat therapy to elicit these adaptations remains unknown. We searched 5 databases for original research, screening 2,913 studies and identifying 18 eligible studies. Heat therapies included Waon therapy, balneotherapy, water perfused trousers, Finnish sauna, and foot immersion. Interventions were administered across various time frames (20- to 90-min) and performed 3 to 7 times per week, for durations of 2- to 8-weeks. The studies collectively involved a diverse population (mean age: 67 (10) years) with cardiovascular diseases. Heat therapy was consistently shown to improve ejection fraction, flow-mediated dilation, brain natriuretic peptide levels, New York Heart Association classification, and six-minute walk distance. However, positive effects on resting heart rate and blood pressure were infrequently observed, and thermoregulatory responses scarcely reported. Heat therapy may increase sweat rate during heat exposure and reduce resting core temperature, but adaptive skin blood flow responses were not observed. Passive heat therapy shows promising utility in patients with cardiovascular disease, while secondary benefits such as markers of thermoregulatory adaptation may also be observed, these require further investigation.

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被动热治疗心血管疾病:目前的证据和未来的方向。
被动热疗法作为一种促进心血管、生理和较小程度的体温调节适应的干预手段,在心血管疾病患者中越来越受欢迎。尽管如此,热疗诱导这些适应的功效仍然未知。我们检索了5个数据库的原始研究,筛选了2913项研究,确定了18项符合条件的研究。热疗法包括温疗、浴疗、水灌注裤、芬兰桑拿和足浸。干预措施在不同的时间框架(20至90分钟)进行,每周进行3至7次,持续时间为2至8周。这些研究总共涉及了不同的心血管疾病人群(平均年龄:67(10)岁)。热疗法一直被证明可以改善射血分数、血流介导的舒张、脑利钠肽水平、纽约心脏协会分类和6分钟步行距离。然而,对静息心率和血压的积极影响很少观察到,并且很少报道体温调节反应。热疗可能增加热暴露时的排汗率,降低静息核心温度,但未观察到适应性皮肤血流量反应。被动热疗法在心血管疾病患者中显示出很好的应用前景,同时也可能观察到诸如热调节适应标记物等次要益处,这些需要进一步研究。
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