Young Onset Chronic Inflammatory Back Pain: A Diagnostic Dilemma Between Axial Spondylitis and Diffuse Idiopathic Skeletal Hyperostosis.

IF 0.9 Q4 RHEUMATOLOGY Modern rheumatology case reports Pub Date : 2025-01-17 DOI:10.1093/mrcr/rxaf002
Rajaie Namas, Sarah Al Qassimi, Jawahir Alameri, Fatema Alawadhi, Esat Memisoglu, Ahlam Al Marzooqi
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Abstract

Diffuse idiopathic skeletal hyperostosis (DISH) and axial spondyloarthritis (axSpA) share similarities in both clinical presentation and radiological findings, making the diagnostic process challenging. We report the case of a 30-year-old male with a longstanding history of back pain with an initial diagnosis of young-onset DISH. However, a diagnosis of axSpA was ultimately pursued based on his age and clinical presentation. This was further supported by improvement in both ASDAS-ESR and ASDAS-CRP scores at his 6- and 12-month follow ups on ixekizumab. Early and accurate diagnosis of axSpA, followed by appropriate treatment, is essential in preventing complications and improving patient outcomes.

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年轻发病的慢性炎症性背痛:轴性脊柱炎和弥漫性特发性骨骼增生之间的诊断困境。
弥漫性特发性骨骼肥大症(DISH)和轴性脊柱炎(axSpA)在临床表现和影像学表现上有相似之处,这使得诊断过程具有挑战性。我们报告的情况下,一个30岁的男性与一个长期的历史背部疼痛的初步诊断年轻发作DISH。然而,最终根据他的年龄和临床表现进行了axSpA的诊断。在ixekizumab的6个月和12个月随访中,ASDAS-ESR和ASDAS-CRP评分的改善进一步支持了这一点。axSpA的早期准确诊断和适当治疗对于预防并发症和改善患者预后至关重要。
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