Uncomplicated pharyngitis due to family transmission of hypervirulent Klebsiella pneumoniae.

IF 3.7 3区 医学 Q2 INFECTIOUS DISEASES European Journal of Clinical Microbiology & Infectious Diseases Pub Date : 2025-01-23 DOI:10.1007/s10096-025-05043-6
Hannah K Gray, Sanchi Malhotra, Shekina Gonzalez-Ferrer, Gregory D Whitehill, Alisa C Chalmers, Shangxin Yang
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引用次数: 0

Abstract

We describe two cases of uncomplicated pharyngitis caused by hypervirulent Klebsiella pneumoniae (hvKp) in a family, initially in an immunocompetent adolescent, followed by possible household spread resulting in similar presentations in the patient's parent. Genomic analysis confirmed hvKp from the two cases were genetically identical and typed as K2-ST3252. Nasopharyngeal carriage and respiratory secretion/droplet may play an important yet underrecognized role in the transmission of hvKp. Enhancing routine screening for hvKp in the upper respiratory culture, followed by genotyping provides an effective pathway for early diagnosis.

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来源期刊
CiteScore
10.40
自引率
2.20%
发文量
138
审稿时长
1 months
期刊介绍: EJCMID is an interdisciplinary journal devoted to the publication of communications on infectious diseases of bacterial, viral and parasitic origin.
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