Tuberculosis in the US Kidney Failure Population.

IF 9.4 1区 医学 Q1 UROLOGY & NEPHROLOGY Journal of The American Society of Nephrology Pub Date : 2025-01-23 DOI:10.1681/ASN.0000000621
Kimberly R Schildknecht, Molly Deutsch-Feldman, Jason Cummins, Divia P Forbes, Maryam B Haddad, Ibironke W Apata, Jonathan M Wortham
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美国肾衰竭人群中的肺结核。
背景:慢性肾脏疾病(CKD)患者在感染结核分枝杆菌后发展为结核病的风险较高。我们对肾衰竭患者中结核病的全国发病率进行了估计和描述。方法:我们对2010年至2021年间美国报告的一例结核病患者进行了横断面描述性分析。我们根据报告的肾衰竭状况对所有肺结核患者进行分层。主要终点是肾衰竭患者的结核发病率。我们还比较了报告肾衰竭状态的肺结核患者的特征。结果:2010年至2021年间,约有3%(111,155人中的2,892人)被诊断患有结核病,同时也患有肾衰竭。每年的结核病发病率为每10万肾衰竭患者26.1至45.4例,每10万非肾衰竭患者2.1至3.5例。在肾衰竭患者中,924人(32%)仅患有肺外结核,近40%死亡:286人死后被诊断为结核病,792人在治疗期间死亡。结核病和肾衰竭患者的结核菌素皮肤试验结果假阴性的流行率(39%)约为单独结核病患者(20%)的两倍。结论:2010年至2021年间,美国肾衰竭患者的结核病发病率是非肾衰竭患者的10倍。
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来源期刊
Journal of The American Society of Nephrology
Journal of The American Society of Nephrology 医学-泌尿学与肾脏学
CiteScore
22.40
自引率
2.90%
发文量
492
审稿时长
3-8 weeks
期刊介绍: The Journal of the American Society of Nephrology (JASN) stands as the preeminent kidney journal globally, offering an exceptional synthesis of cutting-edge basic research, clinical epidemiology, meta-analysis, and relevant editorial content. Representing a comprehensive resource, JASN encompasses clinical research, editorials distilling key findings, perspectives, and timely reviews. Editorials are skillfully crafted to elucidate the essential insights of the parent article, while JASN actively encourages the submission of Letters to the Editor discussing recently published articles. The reviews featured in JASN are consistently erudite and comprehensive, providing thorough coverage of respective fields. Since its inception in July 1990, JASN has been a monthly publication. JASN publishes original research reports and editorial content across a spectrum of basic and clinical science relevant to the broad discipline of nephrology. Topics covered include renal cell biology, developmental biology of the kidney, genetics of kidney disease, cell and transport physiology, hemodynamics and vascular regulation, mechanisms of blood pressure regulation, renal immunology, kidney pathology, pathophysiology of kidney diseases, nephrolithiasis, clinical nephrology (including dialysis and transplantation), and hypertension. Furthermore, articles addressing healthcare policy and care delivery issues relevant to nephrology are warmly welcomed.
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