Lymph Node Staging and Treatment in Pediatric Patients With Soft Tissue Sarcomas: A Consensus Opinion From the Children's Oncology Group, European paediatric Soft Tissue Sarcoma Study Group, and the Cooperative Weichteilsarkom Studiengruppe

IF 2.3 3区医学 Q2 HEMATOLOGY Pediatric Blood & Cancer Pub Date : 2025-01-23 DOI:10.1002/pbc.31538

Sheila Terwisscha van Scheltinga, Reineke A. Schoot, Jonathan C. Routh, Guido Seitz, Simon C. Kao, Bart de Keizer, Barry Shulkin, Roelof van Ewijk, Beth McCarville, Dana Casey, Wendy Allen-Rhoades, Federico Mercolini, Hans Merks, Daniel Orbach, Tejas Kapadia, David O. Walterhouse, Raquel Davila Fajardo, Laura Hiemcke-Jiwa, Christiane Franzius, Federica De Corti, Vivian Tang, Jonathan Metts, Saphna Oberoi, Christian Vokuhl, Roshni Dasgupta, Suzi Birz, David Rodeberg

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Abstract

Accurate staging of nodal involvement in pediatric sarcoma patients is important to determine correct systemic and local therapy, with the goal to reduce subsequent recurrences. However, differences in lymph node staging strategies, definitions, and treatment protocols between the Children's Oncology Group (COG), European paediatric Soft tissue sarcoma Study Group (EpSSG), and the Cooperative Weichteilsarkom Studiengruppe (CWS) complicate comparisons. In this article, we aim to establish internationally recognized recommendations for lymph node assessment and treatment of children and adolescents diagnosed with rhabdomyosarcoma (RMS) and non-rhabdomyosarcoma soft tissue sarcoma (NRSTS) according to the Consensus Conference Standard Operating Procedure methodology.

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小儿软组织肉瘤患者的淋巴结分期和治疗：儿童肿瘤学组、欧洲小儿软组织肉瘤研究组和Weichteilsarkom合作研究小组的共识意见。

小儿肉瘤患者淋巴结受累的准确分期对于确定正确的全身和局部治疗是很重要的，目的是减少随后的复发。然而，儿童肿瘤组（COG）、欧洲儿科软组织肉瘤研究组（EpSSG）和德国合作研究小组（CWS）在淋巴结分期策略、定义和治疗方案上的差异使比较变得复杂。在本文中，我们的目标是根据共识会议标准操作程序的方法，建立国际公认的诊断为横纹肌肉瘤（RMS）和非横纹肌肉瘤软组织肉瘤（NRSTS）的儿童和青少年淋巴结评估和治疗建议。

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来源期刊

Pediatric Blood & Cancer 医学-小儿科

CiteScore

4.90

自引率

9.40%

发文量

546

审稿时长

1.5 months

期刊介绍： Pediatric Blood & Cancer publishes the highest quality manuscripts describing basic and clinical investigations of blood disorders and malignant diseases of childhood including diagnosis, treatment, epidemiology, etiology, biology, and molecular and clinical genetics of these diseases as they affect children, adolescents, and young adults. Pediatric Blood & Cancer will also include studies on such treatment options as hematopoietic stem cell transplantation, immunology, and gene therapy.