The Review of Modified Intersphincteric Resection in the Treatment of Ultra-Low Rectal Cancer.

IF 4.7 2区 医学 Q2 ONCOLOGY Current Treatment Options in Oncology Pub Date : 2025-02-01 Epub Date: 2025-01-23 DOI:10.1007/s11864-025-01291-y
Danni Li, Xi Xiong, Pan Diao, Jitao Hu, Wenbo Niu, Guiying Wang, Baokun Li
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Abstract

Opinion statement: Colorectal cancer is the third leading cause of cancer death worldwide. In China, the incidence and mortality of colorectal cancer are increasing, in which low rectal cancer is more common. Ultra-low rectal cancer refers to rectal cancer where the distance between the tumor and the anus is less than 5 cm, it accounts for about 70%-80% of rectal tumors. Intersphincteric resection (ISR), an important technical means for anal preservation of ultra-low rectal cancer, although could reduce the pain of patients during the surgical process, increase the anal preservation rate of patients and improve the life quality of patients, still has many adverse effects such as the high incidence of anorectal anastomotic leakage and high anterior resection syndrome. Many modified ISRs have emerged due to the limitations and adverse reactions of traditional ISR surgery. the purpose of this article is to review the progress of ISR surgery to improve its use in treatment.

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改良括约肌间切除术治疗超低位直肠癌的研究进展。
意见声明:结直肠癌是全世界癌症死亡的第三大原因。在中国,结直肠癌的发病率和死亡率都在不断上升,其中低位直肠癌更为常见。超低位直肠癌是指肿瘤与肛门之间的距离小于5厘米的直肠癌,约占直肠肿瘤的70%-80%。括约肌间切除术(intersphincterectomy, ISR)是超低位直肠癌保肛的重要技术手段,虽然可以减轻患者手术过程中的疼痛,提高患者的保肛率,改善患者的生活质量,但仍存在肛门直肠吻合口漏发生率高、前切综合征高等诸多不良反应。由于传统ISR手术的局限性和不良反应,出现了许多改良的ISR手术。本文的目的是回顾ISR手术的进展,以提高其在治疗中的应用。
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来源期刊
CiteScore
7.10
自引率
0.00%
发文量
113
审稿时长
>12 weeks
期刊介绍: This journal aims to review the most important, recently published treatment option advances in the field of oncology. By providing clear, insightful, balanced contributions by international experts, the journal intends to facilitate worldwide approaches to cancer treatment. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as endocrine tumors, lymphomas, neuro-oncology, and cancers of the breast, head and neck, lung, skin, gastrointestinal tract, and genitourinary region. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. We also provide commentaries from well-known oncologists, and an international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research.
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