{"title":"Surgical outcomes of subclavian steal syndrome combined with carotid artery stenosis: A single-center retrospective observational study.","authors":"Haotian Huanggu, Guangchao Gu, Fangda Li, Rong Zeng, Jiang Shao, Xiaojun Song, Zhili Liu, Yuehong Zheng","doi":"10.1177/00368504241307470","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To explore the prevalence and risk factors of carotid artery (CA) stenosis among subclavian steal syndrome (SSS) patients and to record their prognoses.</p><p><strong>Methods: </strong>This observational study was retrospective. From January 2015 to October 2022, 169 patients were diagnosed with SSS. Among them, 51 combined with CA stenosis have surgical indications for both diseases. In this cohort, 24 were treated for subclavian artery (23 endovascular, 1 open), 12 for CA (6 endovascular, 6 open), and 5 for both (1 endovascular, 1 open, 3 hybrid). The primary end point was mortality, and the secondary end points were vessel re-stenosis and other complications. Patients were followed up through outpatient, online, or telephone.</p><p><strong>Results: </strong>Compared with simple SSS, patients who suffered from both were older (60.51 ± 9.304 versus 66.69 ± 7.921, <i>P</i> < 0.001) and more males (57.6% versus 86.3%, <i>P</i> < .001). Besides, they presented a higher prevalence of hyperhomocysteinemia (<i>P</i> = .015), diabetes mellitus (<i>P</i> = .036), and CVA/TIA (<i>P</i> = .036). No patient died within 30 days after surgery; four complications occurred (1 stroke, 1 hearing loss, 1 TIA, 1 infection). During a median follow-up of 37.6 months, two patients died without relation to the operation, three appeared in-stent restenosis, and one developed contrast nephropathy.</p><p><strong>Discussion: </strong>This study observed and analyzed different intervention methods and their prognosis in SSS combined with CA stenosis patients, and due to the limited number of participants, more data support would be needed.</p><p><strong>Conclusions: </strong>The management of SSS patients combined with CA stenosis is more challenging compared to simple SSS. Our research demonstrated different surgical methods and their prognosis.</p>","PeriodicalId":56061,"journal":{"name":"Science Progress","volume":"108 1","pages":"368504241307470"},"PeriodicalIF":2.9000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11758550/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Science Progress","FirstCategoryId":"103","ListUrlMain":"https://doi.org/10.1177/00368504241307470","RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MULTIDISCIPLINARY SCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
Objective: To explore the prevalence and risk factors of carotid artery (CA) stenosis among subclavian steal syndrome (SSS) patients and to record their prognoses.
Methods: This observational study was retrospective. From January 2015 to October 2022, 169 patients were diagnosed with SSS. Among them, 51 combined with CA stenosis have surgical indications for both diseases. In this cohort, 24 were treated for subclavian artery (23 endovascular, 1 open), 12 for CA (6 endovascular, 6 open), and 5 for both (1 endovascular, 1 open, 3 hybrid). The primary end point was mortality, and the secondary end points were vessel re-stenosis and other complications. Patients were followed up through outpatient, online, or telephone.
Results: Compared with simple SSS, patients who suffered from both were older (60.51 ± 9.304 versus 66.69 ± 7.921, P < 0.001) and more males (57.6% versus 86.3%, P < .001). Besides, they presented a higher prevalence of hyperhomocysteinemia (P = .015), diabetes mellitus (P = .036), and CVA/TIA (P = .036). No patient died within 30 days after surgery; four complications occurred (1 stroke, 1 hearing loss, 1 TIA, 1 infection). During a median follow-up of 37.6 months, two patients died without relation to the operation, three appeared in-stent restenosis, and one developed contrast nephropathy.
Discussion: This study observed and analyzed different intervention methods and their prognosis in SSS combined with CA stenosis patients, and due to the limited number of participants, more data support would be needed.
Conclusions: The management of SSS patients combined with CA stenosis is more challenging compared to simple SSS. Our research demonstrated different surgical methods and their prognosis.
目的：探讨锁骨下窃血综合征（SSS）患者颈动脉（CA）狭窄的发生率及危险因素，并记录其预后。方法：本观察性研究为回顾性研究。2015年1月至2022年10月，169例患者被诊断为SSS。其中合并CA狭窄51例，两种疾病均有手术指征。在该队列中，24例治疗锁骨下动脉（23例血管内，1例开放），12例治疗CA（6例血管内，6例开放），5例治疗两者（1例血管内，1例开放，3例混合）。主要终点是死亡率，次要终点是血管再狭窄和其他并发症。通过门诊、在线或电话对患者进行随访。结果：与单纯SSS相比，两组患者年龄（60.51±9.304 vs 66.69±7.921,P P P = 0.015）、糖尿病（P = 0.036）、CVA/TIA （P = 0.036）差异显著。术后30天内无患者死亡；发生4例并发症（1例卒中、1例听力损失、1例TIA、1例感染）。在37.6个月的中位随访期间，2例患者死亡，与手术无关，3例出现支架内再狭窄，1例发生造影剂肾病。讨论：本研究对SSS合并CA狭窄患者的不同干预方法及其预后进行了观察和分析，由于参与人数有限，需要更多的数据支持。结论：与单纯SSS相比，合并CA狭窄的SSS患者的治疗更具挑战性。我们的研究显示了不同的手术方法及其预后。
期刊介绍：
Science Progress has for over 100 years been a highly regarded review publication in science, technology and medicine. Its objective is to excite the readers'' interest in areas with which they may not be fully familiar but which could facilitate their interest, or even activity, in a cognate field.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
