Cutaneous Involvement of the Ear as the Sole Presenting Symptom in Recurrent Chronic Lymphocytic Leukemia: A Case Report.

Stephanie S Kim, Aravindhan Sriharan, Andrew Y Lee, Ryan R McCool
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Abstract

Cutaneous involvement of chronic lymphocytic leukemia (CLL) is rare but has been previously documented to involve the head and neck region. Generally, involvement to the ears is limited to the ear lobule; however, this study presents a unique case of recurrent CLL with cutaneous involvement overlying the auricular ear. The presentation was initially concerning for possible perichondritis but remained unresponsive to antibiotics and steroids. Eventual punch biopsy confirmed the recurrent CLL, although the lesion also presented with unique pathology, notably associated granulomata. This case demonstrates auricular involvement of CLL with unique pathology and highlights the importance of a widened differential and early, definitive tissue biopsy when evaluating refractory inflammation of the external ear.

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耳部皮肤受累是复发性慢性淋巴细胞白血病的唯一症状:1例报告。
慢性淋巴细胞白血病(CLL)的皮肤累及是罕见的,但已经有文献记载累及头颈部区域。一般来说,耳朵的受累仅限于耳小叶;然而,这项研究提出了一个独特的病例复发CLL与皮肤累及覆盖耳廓。最初的表现是担心可能的软骨膜炎,但仍然对抗生素和类固醇无反应。最终穿孔活检证实了复发性CLL,尽管病变也表现出独特的病理,特别是相关肉芽肿。本病例显示了CLL累及耳部的独特病理,强调了在评估外耳难治性炎症时,扩大鉴别和早期明确组织活检的重要性。
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