Comparative In Vitro Study of Sol-Gel-Derived Bioactive Glasses Incorporated into Dentin Adhesives: Effects on Remineralization and Mechanical Properties of Dentin.

IF 5.2 3区 医学 Q1 ENGINEERING, BIOMEDICAL Journal of Functional Biomaterials Pub Date : 2025-01-16 DOI:10.3390/jfb16010029
In-Seong Park, Hyun-Jung Kim, Jiyoung Kwon, Duck-Su Kim
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Abstract

To overcome limitations of dentin bonding due to collagen degradation at a bonded interface, incorporating bioactive glass (BAG) into dentin adhesives has been proposed to enhance remineralization and improve bonding durability. This study evaluated sol-gel-derived BAGs (BAG79, BAG87, BAG91, and BAG79F) and conventional melt-quenched BAG (BAG45) incorporated into dentin adhesive to assess their remineralization and mechanical properties. The BAGs were characterized by using field-emission scanning electron microscopy (FE-SEM) and transmission electron microscopy for surface morphology. The surface area was measured by the Brunauer-Emmett-Teller method. X-ray diffraction (XRD) analysis was performed to determine the crystalline structure of the BAGs. Adhesive surface analysis was performed after approximating each experimental dentin adhesive and demineralized dentin by using FE-SEM. The elastic modulus of the treated dentin was measured after BAG-containing dentin adhesive application. The sol-gel-derived BAGs exhibited larger surface areas (by 400-600 times) than conventional BAG, with BAG87 displaying the largest surface area. XRD analysis indicated more pronounced and rapid formation of hydroxyapatite in the sol-gel BAGs. Dentin with BAG87-containing adhesive exhibited the highest elastic modulus. The incorporation of sol-gel-derived BAGs, especially BAG87, into dentin adhesives enhances the remineralization and mechanical properties of adhesive-dentin interfaces.

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溶胶-凝胶生物活性玻璃与牙本质黏合剂的体外对比研究:对牙本质再矿化和力学性能的影响。
为了克服胶原降解对牙本质粘接的限制,人们提出将生物活性玻璃(BAG)加入牙本质粘接剂中,以增强再矿化和提高粘接的耐久性。本研究评估了溶胶-凝胶衍生BAG (BAG79、BAG87、BAG91和BAG79F)和常规熔淬BAG (BAG45)与牙本质粘接剂的再矿化和力学性能。采用场发射扫描电镜(FE-SEM)和透射电镜对其表面形貌进行了表征。表面积采用brunauer - emmet - teller法测量。用x射线衍射(XRD)分析了袋子的晶体结构。利用FE-SEM对各实验牙本质黏合剂和脱矿牙本质进行近似分析,并对黏合剂表面进行分析。使用含bag的牙本质粘接剂后,测量处理后牙本质的弹性模量。溶胶-凝胶法制备的塑料袋比传统的塑料袋表面积大400-600倍,其中BAG87的表面积最大。XRD分析表明,溶胶-凝胶袋中羟基磷灰石的形成更为明显和迅速。含bag87胶粘剂的牙本质弹性模量最高。溶胶-凝胶衍生的bag,特别是BAG87,加入到牙本质粘接剂中,增强了粘接剂-牙本质界面的再矿化和力学性能。
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来源期刊
Journal of Functional Biomaterials
Journal of Functional Biomaterials Engineering-Biomedical Engineering
CiteScore
4.60
自引率
4.20%
发文量
226
审稿时长
11 weeks
期刊介绍: Journal of Functional Biomaterials (JFB, ISSN 2079-4983) is an international and interdisciplinary scientific journal that publishes regular research papers (articles), reviews and short communications about applications of materials for biomedical use. JFB covers subjects from chemistry, pharmacy, biology, physics over to engineering. The journal focuses on the preparation, performance and use of functional biomaterials in biomedical devices and their behaviour in physiological environments. Our aim is to encourage scientists to publish their results in as much detail as possible. Therefore, there is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. Several topical special issues will be published. Scope: adhesion, adsorption, biocompatibility, biohybrid materials, bio-inert materials, biomaterials, biomedical devices, biomimetic materials, bone repair, cardiovascular devices, ceramics, composite materials, dental implants, dental materials, drug delivery systems, functional biopolymers, glasses, hyper branched polymers, molecularly imprinted polymers (MIPs), nanomedicine, nanoparticles, nanotechnology, natural materials, self-assembly smart materials, stimuli responsive materials, surface modification, tissue devices, tissue engineering, tissue-derived materials, urological devices.
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