Endovascular therapy is effective in patients with post-thrombotic syndrome based on anatomical classification: a multi-center experience.

Abstract

Objective: In this study, we aimed to retrospectively review patients with post-thrombotic syndrome (PTS) and investigate its long-term outcomes, and a novel classification were presented across multiple institutions.

Methods: We retrospectively evaluated patients with PTS who underwent endovascular therapy at two institutions between January 2018 and September 2023. Baseline patient demographics, lesion characteristics, and in-hospital and follow-up outcomes were collected and analyzed retrospectively.

Results: 83 patients (86 limbs) patients suffered PTS received endovascular related surgery at the two institutions. The lesions were summarized into two categories: sufficient or insufficient inflow according to digital subtraction angiography(DSA). 77 limbs (89.53%) underwent successful endovascular treatment including 46 limbs receiving percutaneous transluminal angioplasty (PTA) and stent implantation ,and 31 limbs undergoing PTA without stent deployment was mainly contributed to insufficient inflow. The mean follow-up time was 23.44±16.91 months (range, 6-60 months) in stent implantation cohort. In-stent restenosis and an occlusive endograft edge were observed in two cases, respectively. No other stent-related complications, such as fractures or migration, were noted in any patient during the follow-up period.

Conclusions: Endovascular technique was safe and effective for the treatment of PTS and showed promising long-term prognosis. The novel classification of PTS might be feasible for the strategy of endovascular treatment.