{"title":"Age predicts peak gamma frequency and N1 amplitude of visual evoked potential.","authors":"Abdullah Bin Dawood","doi":"10.1186/s12868-024-00917-5","DOIUrl":null,"url":null,"abstract":"<p><p>The current study investigated whether the age of healthy adults could predict the peak gamma frequency and the peak amplitudes of VEP components (N1, P2). 49 healthy participants (aged between 19 and 52 years) underwent EEG recordings during a visual task eliciting clear gamma frequency oscillations and VEP activities. After eliminating noisy and outlier data, data from 41 participants were analysed using simple linear regression. The results indicated that age was a significant predictor of peak gamma frequency and the peak amplitude of VEP-N1 but not the peak amplitude of VEP-P2. Age was negatively associated with peak gamma frequency and the peak amplitude of VEP-N1. These findings support previous research indicating that ageing is associated with decreased cortical inhibition, highlighting the importance of GABA in maintaining cortical E-I balance.</p>","PeriodicalId":9031,"journal":{"name":"BMC Neuroscience","volume":"26 1","pages":"7"},"PeriodicalIF":2.4000,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763129/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"BMC Neuroscience","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1186/s12868-024-00917-5","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"NEUROSCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
The current study investigated whether the age of healthy adults could predict the peak gamma frequency and the peak amplitudes of VEP components (N1, P2). 49 healthy participants (aged between 19 and 52 years) underwent EEG recordings during a visual task eliciting clear gamma frequency oscillations and VEP activities. After eliminating noisy and outlier data, data from 41 participants were analysed using simple linear regression. The results indicated that age was a significant predictor of peak gamma frequency and the peak amplitude of VEP-N1 but not the peak amplitude of VEP-P2. Age was negatively associated with peak gamma frequency and the peak amplitude of VEP-N1. These findings support previous research indicating that ageing is associated with decreased cortical inhibition, highlighting the importance of GABA in maintaining cortical E-I balance.
期刊介绍：
BMC Neuroscience is an open access, peer-reviewed journal that considers articles on all aspects of neuroscience, welcoming studies that provide insight into the molecular, cellular, developmental, genetic and genomic, systems, network, cognitive and behavioral aspects of nervous system function in both health and disease. Both experimental and theoretical studies are within scope, as are studies that describe methodological approaches to monitoring or manipulating nervous system function.
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