Ahmed H Bakheit, Khaled Abdelrazaq, Hamad M Alkahtani, Fatemah S Albalawi, Yousef A Bin Jardan, Abdulrahman Al-Majed
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Abstract
This comprehensive drug profile provides a detailed exploration of Dronedarone, an antiarrhythmic medication used for regulating irregular heartbeats. This chapter covers various aspects of Dronedarone, including its nomenclature, formulae, physical characteristics, methods of preparation, and analytical methods. The nomenclature section presents the IUPAC and nonproprietary names of Dronedarone, along with its proprietary names. The empirical formula, molecular weight, and CAS number are provided for both Dronedarone and its hydrochloride salt. The document also explores the physical characteristics, including color, form, and optical activity, as well as the melting point, solubility, and spectroscopic analysis. Stability, clinical applications, pharmacology, mechanism of action, and pharmacokinetics are discussed.
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