Electroencephalographic Features of Presumed Hepatic Encephalopathy in a Pediatric Dog with a Portosystemic Shunt-A Case Report.

IF 3.4 3区 生物学 Q1 BIOLOGY Life-Basel Pub Date : 2025-01-16 DOI:10.3390/life15010107
Raluca Adriana Ștefănescu, Vasile Boghian, Gheorghe Solcan, Mario Darius Codreanu, Mihai Musteata
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Abstract

Hepatic encephalopathy (HE) in dogs is a metabolic disorder of the central nervous system that occurs secondarily to liver dysfunctions, whether due to acquired or congenital causes. A portosystemic shunt is the presence of abnormal communications between the hepatic vessels (portal and suprahepatic veins). As a result of this, the blood brought from the digestive tract through the portal vein bypasses the liver, and the unmetabolized components of the portal bloodstream enter directly into systemic circulation, causing clinical symptoms of metabolic encephalopathy (HE). A 3-month-old Bichon canine patient with a history of seizures secondarily to a portosystemic shunt (PS), confirmed through color Doppler ultrasound exam and computed tomography, was presented for evaluation. The typical electroencephalographic (EEG) traces recorded were characterized by the presence of bilateral symmetrical triphasic waves, resembling non-convulsive status epilepticus. The presence of this EEG pattern is useful in choosing the best therapeutic option in order to not accentuate the HE sings and, consequently, to decrease the mortality risk due to a prolonged status epilepticus.

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假定肝性脑病的小儿犬伴门静脉系统分流的脑电图特征。
肝性脑病(HE)是一种继发于肝功能障碍的中枢神经系统代谢紊乱,可由后天或先天原因引起。门静脉系统分流是指肝血管(门静脉和肝上静脉)之间存在异常的交通。因此,从消化道经门静脉带入的血液绕过肝脏,门静脉血流中未代谢的成分直接进入体循环,引起代谢性脑病(HE)的临床症状。一个3个月大的比雄犬患者,有继发于门静脉系统分流(PS)的癫痫发作史,通过彩色多普勒超声检查和计算机断层扫描证实,提出评估。典型的脑电图(EEG)记录的特征是存在双侧对称的三相波,类似于非惊厥性癫痫持续状态。这种脑电图模式的存在有助于选择最佳治疗方案,以避免加重HE唱,从而降低由于长时间癫痫持续状态而导致的死亡风险。
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来源期刊
Life-Basel
Life-Basel Biochemistry, Genetics and Molecular Biology-General Biochemistry,Genetics and Molecular Biology
CiteScore
4.30
自引率
6.20%
发文量
1798
审稿时长
11 weeks
期刊介绍: Life (ISSN 2075-1729) is an international, peer-reviewed open access journal of scientific studies related to fundamental themes in Life Sciences, especially those concerned with the origins of life and evolution of biosystems. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. There is no restriction on the length of the papers.
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