Central Corneal Subepithelial Haze Following Keratoplasty With Interrupted Sutures: A Novel Clinical Finding.

Abstract

Purpose: This study aims to describe a newly identified clinical finding of central corneal subepithelial haze following keratoplasty (both penetrating and lamellar) with interrupted sutures, and to explore its causes and management strategies.

Methods: Case series.

Results: The study included 7 males and 3 females, with an average age of 24.89 ± 6.57 years. Eight eyes underwent lamellar keratoplasty, and two underwent penetrating keratoplasty. Subepithelial haze appeared between 2 and 5 months postoperatively, associated with central corneal steepening. The mean BCVA improved from 0.88 ± 0.50 logMAR preoperatively to 0.51 ± 0.20 at haze documentation and 0.50 ± 0.16 after haze resolution. Selective suture removal resulted in haze resolution in 9 eyes, while delayed intervention in one case led to permanent scarring.

Conclusion: Central corneal subepithelial haze following keratoplasty with interrupted sutures is linked to suture tension and central corneal steepening. Early suture adjustment or removal is essential to prevent permanent scarring. Further studies are needed to better understand this complication's pathophysiology.