Gender differences in cognitive impairment among the elderly in rural West Texas counties.

IF 3.1 3区 医学 Q2 NEUROSCIENCES Journal of Alzheimer's Disease Pub Date : 2025-02-01 Epub Date: 2025-01-26 DOI:10.1177/13872877241305772
Hafiz Khan, Fardous Farhana, Fahad Mostafa, Aamrin Rafiq, Effat W Nizia, Zawah Zabin, Rumana Atique, Megan Dauenhauer, Opemipo Omotara, Atqa Mujtaba, Komaraiah Palle, P Hemachandra Reddy
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Abstract

Background: The prevalence of Alzheimer's disease or dementia in the elderly population has been increasing both nationally and globally. Males and females are impacted differently when it comes to cognitive health, and this can be influenced by various risk factors.

Objective: This study highlights the sociodemographic, chronic disease, and genetic biomarker risk factors associated with gender differences and cognitive impairments in the elderly population living in Cochran, Parmer, and Bailey counties of rural West Texas.

Methods: Cross tabulation, Pearson's chi-squared, two sample proportions, binary logistic regression, and multinomial logistic regression were utilized to analyze data. SPSS software was used to detect significant risk factors.

Results: Using a bivariate logistic regression, the age group 70 and above of males and females for the Cochran and Parmer counties was found significantly associated with cognitive impairment. Anxiety, depression, diabetes, and cardiovascular disease were found to be significantly associated with an increased risk of cognitive impairment in females in Parmer County. Gender differences were observed in Cochran County for smoking but females in Bailey County were found to be more tobacco-dependent compared to other counties. However, in Cochran County the prevalence of cognitive impairment with rates of 66% for males and 70% for females was observed to be significantly lower in hypertensive group who consumed modified diet.

Conclusions: Gender-based disparities in cognitive impairment are essential for gaining more insights into Alzheimer's disease or dementia prevention and advancement of healthcare and medical approaches in the underserved rural communities of West Texas.

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西德克萨斯州农村老年人认知障碍的性别差异。
背景:无论是在国家还是全球,老年人群中阿尔茨海默病或痴呆症的患病率都在增加。在认知健康方面,男性和女性受到的影响不同,这可能受到各种风险因素的影响。目的:本研究强调了生活在德克萨斯州西部农村Cochran、Parmer和Bailey县的老年人口中与性别差异和认知障碍相关的社会人口学、慢性病和遗传生物标志物风险因素。方法:采用交叉表法、Pearson卡方法、双样本比例法、二元logistic回归法、多项logistic回归法对数据进行分析。采用SPSS软件检测显著危险因素。结果:采用双变量logistic回归分析,Cochran县和Parmer县70岁及以上的男性和女性与认知障碍显著相关。焦虑、抑郁、糖尿病和心血管疾病被发现与Parmer县女性认知障碍风险增加显著相关。科克伦县的吸烟情况存在性别差异,但贝利县的女性吸烟依赖程度高于其他县。然而,在科克伦县,认知障碍的患病率为男性66%,女性70%,观察到高血压患者饮食调整后显著降低。结论:基于性别的认知障碍差异对于在西德克萨斯州服务不足的农村社区获得更多关于阿尔茨海默病或痴呆症预防的见解以及医疗保健和医疗方法的进步至关重要。
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来源期刊
Journal of Alzheimer's Disease
Journal of Alzheimer's Disease 医学-神经科学
CiteScore
6.40
自引率
7.50%
发文量
1327
审稿时长
2 months
期刊介绍: The Journal of Alzheimer''s Disease (JAD) is an international multidisciplinary journal to facilitate progress in understanding the etiology, pathogenesis, epidemiology, genetics, behavior, treatment and psychology of Alzheimer''s disease. The journal publishes research reports, reviews, short communications, hypotheses, ethics reviews, book reviews, and letters-to-the-editor. The journal is dedicated to providing an open forum for original research that will expedite our fundamental understanding of Alzheimer''s disease.
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