Increasing trends of cannabinoid hyperemesis syndrome in youth: The grass is not always greener.

Abstract

This study investigated trends in suspected cannabinoid hyperemesis syndrome (CHS)-related emergency department visits among youth (15-24 years old) in the United States between 2006 and 2020. Using data from the Nationwide Emergency Room Sample, over 55,000 suspected CHS-related visits were identified, with an average annual increase of 28.1% per year. This aligns with rising cannabis use and potency across the nation. Subjects in the western region, males, and those with public insurance were more likely to present with suspected CHS. These findings highlight the growing public health concern of CHS and emphasize the need for increased awareness among healthcare providers, particularly regarding the potential link between CHS and chronic cannabis use in youth. Further research is needed to understand the underlying mechanisms and risk factors associated with CHS as well as the impact of cannabis public policy on health outcomes.