Pubic symphysitis of enthesitis related arthritis mimicking urinary tract infection in a young boy.

Neha Riswadkar, Rajoo Ramachandaran, Nidarshana Pandian, Mahesh Janarthanan
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Abstract

Enthesitis related arthritis (ERA) is a specific type of juvenile idiopathic arthritis (JIA) and ERA typically begins with enthesitis and peripheral arthritis in the lower extremities, progressing later in the disease to sacroiliitis and spinal involvement. The condition has a strong relationship with the HLA-B27 and primarily affects boys between the ages of 13 and 16 years. We describe an unusual presentation of ERA in a young boy with pubic pain and fever, describing its quintessential magnetic resonance imaging (MRI) findings. A child presented to the paediatric outpatient department with fever, insidious onset pubic pain and tenderness with associated leukocytosis and elevated inflammatory markers. MRI of the pelvis revealed bilateral symmetrical bone marrow edema involving the pubic symphysis and inferior pubic rami with para symphyseal edema involving bilateral obturator externus muscle and bilateral adductor longus muscle insertions suggestive of enthesitis of the pubic symphysis. MRI also showed sacroiliitis and enthesitis at other sites. HLA-B27 was positive. The patient responded well to a short course of steroids and maintained remission with tumour necrosis factor alpha inhibitors.

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与粘连相关的关节炎(ERA)是幼年特发性关节炎(JIA)的一种特殊类型,ERA 通常以下肢粘连和外周关节炎起病,后期发展为骶髂关节炎和脊柱受累。该病与 HLA-B27 关系密切,主要影响 13 至 16 岁的男孩。我们描述了一名患有ERA的男孩的不寻常表现,他伴有耻骨痛和发热,并描述了其典型的磁共振成像(MRI)结果。一名儿童因发热、隐匿性阴部疼痛和触痛,伴有白细胞增多和炎症指标升高而到儿科门诊就诊。骨盆核磁共振成像显示耻骨联合和耻骨下缘双侧对称性骨髓水肿,耻骨旁水肿累及双侧闭孔肌外侧和双侧内收肌插入部,提示耻骨联合粘连炎。磁共振成像还显示骶髂关节炎和其他部位的粘连炎。HLA-B27 呈阳性。患者对短期类固醇治疗反应良好,使用肿瘤坏死因子α抑制剂后病情得到缓解。
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