Recent progress in electrochemical rearrangement reactions

Abstract

Rearrangement reactions are among the most critical transformations in synthetic chemistry, enabling the construction of complex molecules from simple starting materials through the cleavage and reformation of chemical bonds. Synthetic electrochemistry, as a sustainable synthesis method, eliminates the need for stoichiometric redox reagents, significantly advancing green chemistry. Over the past decade, numerous electrochemically promoted rearrangement reactions have been developed, demonstrating the broad applicability of electrochemistry in facilitating rearrangement processes. This review highlights the application of electrochemistry in rearrangements, focusing on functional group migrations, ring expansion reactions, and selective migratory cyclization reactions.