Long-term efficacy of superior laryngeal nerve block for the treatment of chronic neurogenic cough.

IF 1.9 3区医学 Q2 OTORHINOLARYNGOLOGY European Archives of Oto-Rhino-Laryngology Pub Date : 2025-01-28 DOI:10.1007/s00405-025-09222-1

Tanner J Diemer, Brian A Keith, Shaun A Nguyen, Ashli K O'Rourke

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引用次数: 0

Abstract

Purpose: The study aimed to evaluate the long-term efficacy and safety of superior laryngeal nerve (SLN) block for treating chronic neurogenic cough (CNC) in a large patient cohort.

Methods: A retrospective review was conducted on patients treated between January 2019 and October 2023. Data collected included patient demographics, number of injections, follow-up times, subjective cough severity, and Leicester Cough Questionnaire (LCQ) scores.

Results: Among 117 patients (76.1% female; mean age 66.1), the median number of injections was 3, with a median follow-up duration of 4 weeks. Subjective improvement was reported in 74.4% of cases, with mild adverse events occurring in 8.4% of injections. Regression analysis showed a strong correlation between decreased subjective severity and time. LCQ scores improved slightly within 1-3 months and 25-40 months.

Conclusion: The findings suggest that SLN blocks effectively reduce subjective severity and improve LCQ scores long-term, with sequential injections potentially reducing chronic steroid use risks. Further prospective studies are recommended to optimize dosing intervals.

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来源期刊

European Archives of Oto-Rhino-Laryngology 医学-耳鼻喉科学

CiteScore

5.30

自引率

7.70%

发文量

537

审稿时长

2-4 weeks

期刊介绍： Official Journal of European Union of Medical Specialists – ORL Section and Board Official Journal of Confederation of European Oto-Rhino-Laryngology Head and Neck Surgery "European Archives of Oto-Rhino-Laryngology" publishes original clinical reports and clinically relevant experimental studies, as well as short communications presenting new results of special interest. With peer review by a respected international editorial board and prompt English-language publication, the journal provides rapid dissemination of information by authors from around the world. This particular feature makes it the journal of choice for readers who want to be informed about the continuing state of the art concerning basic sciences and the diagnosis and management of diseases of the head and neck on an international level. European Archives of Oto-Rhino-Laryngology was founded in 1864 as "Archiv für Ohrenheilkunde" by A. von Tröltsch, A. Politzer and H. Schwartze.