Spatial Epidemiology of Human Papillomavirus Screening Coverage in Mexico, 2013-2019.

Oscar Alejandro Palacios Rodríguez, Miguel Galarde López, Carlos Quezada Sánchez, Antonio Reyna Sevilla
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Abstract

Objective: We aimed to assess the coverage of a Human Papillomavirus (HPV) screening program for each of the 32 federal states of Mexico, as well as the spatial patterns for HPV infections from 2013 to 2019.

Methods: We conducted an exploratory, ecological study on data from a national health program in Mexico during 2013-2019. Adjusted rates per 100,000 females aged 25-64 years were estimated and georeferenced at the national and state level to assess the coverage of the screening program and positive detections of HPV infections. Cluster analysis was used to identify the location, magnitude, and trends of spatial patterns (p <0.05) by year and state.

Results: 2,529,819 screening tests for HPV detection were analyzed (2013-2019). A prevalence of HPV positivity of 11.1% (n= 228,582) was estimated. The number of HPV screening tests decreased from 2,835.4 (2013) to 0.8 (2019) per 100,000 females aged 25 to 64. HPV detection also showed a downward trend. A cluster (p <0.05) associated with a higher probability of detecting HPV infections was identified, comprised of territorially close states.

Conclusion: A decreased coverage of the HPV screening program and geographic differences were identified, suggesting that the existing strategies to prevent and detect HPV infections to accelerate cervical cancer elimination in Mexico need to be further reconsidered.

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2013-2019年墨西哥人乳头瘤病毒筛查覆盖率的空间流行病学分析
目的:我们旨在评估墨西哥32个联邦州中每个州的人乳头瘤病毒(HPV)筛查计划的覆盖率,以及2013年至2019年HPV感染的空间格局。方法:我们对2013-2019年墨西哥国家卫生计划的数据进行了探索性生态学研究。对每10万名25-64岁女性的调整率进行了估计,并在国家和州一级进行了地理参考,以评估筛查计划的覆盖率和HPV感染的阳性检测。聚类分析用于确定空间模式的位置、幅度和趋势(p)。结果:分析了2013-2019年2,529,819例HPV检测筛查试验。HPV阳性的患病率估计为11.1% (n= 228,582)。每10万名25至64岁女性的HPV筛查检测次数从2835.4次(2013年)下降到0.8次(2019年)。HPV检出率也呈下降趋势。结论:发现HPV筛查计划覆盖率下降和地理差异,表明需要进一步重新考虑墨西哥预防和检测HPV感染以加速消除宫颈癌的现有策略。
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来源期刊
CiteScore
2.80
自引率
0.00%
发文量
779
审稿时长
3 months
期刊介绍: Cancer is a very complex disease. While many aspects of carcinoge-nesis and oncogenesis are known, cancer control and prevention at the community level is however still in its infancy. Much more work needs to be done and many more steps need to be taken before effective strategies are developed. The multidisciplinary approaches and efforts to understand and control cancer in an effective and efficient manner, require highly trained scientists in all branches of the cancer sciences, from cellular and molecular aspects to patient care and palliation. The Asia Pacific Organization for Cancer Prevention (APOCP) and its official publication, the Asia Pacific Journal of Cancer Prevention (APJCP), have served the community of cancer scientists very well and intends to continue to serve in this capacity to the best of its abilities. One of the objectives of the APOCP is to provide all relevant and current scientific information on the whole spectrum of cancer sciences. They aim to do this by providing a forum for communication and propagation of original and innovative research findings that have relevance to understanding the etiology, progression, treatment, and survival of patients, through their journal. The APJCP with its distinguished, diverse, and Asia-wide team of editors, reviewers, and readers, ensure the highest standards of research communication within the cancer sciences community across Asia as well as globally. The APJCP publishes original research results under the following categories: -Epidemiology, detection and screening. -Cellular research and bio-markers. -Identification of bio-targets and agents with novel mechanisms of action. -Optimal clinical use of existing anti-cancer agents, including combination therapies. -Radiation and surgery. -Palliative care. -Patient adherence, quality of life, satisfaction. -Health economic evaluations.
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