Unlocking the potential of engineered immune cell therapy for solid tumors

IF 15.7 1区 综合性期刊 Q1 MULTIDISCIPLINARY SCIENCES Nature Communications Pub Date : 2025-01-29 DOI:10.1038/s41467-025-56527-0
Víctor Albarrán-Fernández, Laura Angelats, Julio Delgado, Alena Gros, Álvaro Urbano-Ispizua, Sònia Guedan, Aleix Prat
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Abstract

Adoptive cell therapy has emerged as a promising approach for treating advanced solid malignancies. Genetic engineering techniques represent an exciting area of research for the development of cellular products with enhanced cytotoxicity, phenotype, and metabolism.

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释放工程免疫细胞治疗实体瘤的潜力
过继细胞疗法已成为治疗晚期实体恶性肿瘤的一种很有前途的方法。基因工程技术代表了一个令人兴奋的研究领域,用于开发具有增强细胞毒性,表型和代谢的细胞产物。
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来源期刊
Nature Communications
Nature Communications Biological Science Disciplines-
CiteScore
24.90
自引率
2.40%
发文量
6928
审稿时长
3.7 months
期刊介绍: Nature Communications, an open-access journal, publishes high-quality research spanning all areas of the natural sciences. Papers featured in the journal showcase significant advances relevant to specialists in each respective field. With a 2-year impact factor of 16.6 (2022) and a median time of 8 days from submission to the first editorial decision, Nature Communications is committed to rapid dissemination of research findings. As a multidisciplinary journal, it welcomes contributions from biological, health, physical, chemical, Earth, social, mathematical, applied, and engineering sciences, aiming to highlight important breakthroughs within each domain.
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