I2-Catalyzed benzylation of NH-sulfoximines with diarylmethanes and alkylarenes†

IF 2.7 3区 化学 Q1 CHEMISTRY, ORGANIC Organic & Biomolecular Chemistry Pub Date : 2025-01-16 DOI:10.1039/d4ob01709a
Yiyi Chen , Qisheng Chen , Shuangquan Zhang , Kun Feng , Xianqiang Kong , Xiaohui Chen , Wenjuan Li , Zhong-Yan Cao
{"title":"I2-Catalyzed benzylation of NH-sulfoximines with diarylmethanes and alkylarenes†","authors":"Yiyi Chen ,&nbsp;Qisheng Chen ,&nbsp;Shuangquan Zhang ,&nbsp;Kun Feng ,&nbsp;Xianqiang Kong ,&nbsp;Xiaohui Chen ,&nbsp;Wenjuan Li ,&nbsp;Zhong-Yan Cao","doi":"10.1039/d4ob01709a","DOIUrl":null,"url":null,"abstract":"<div><div>A practical transition metal-free approach for the selective benzylation of NH-sulfoximines has been disclosed by using simple elemental iodine as the catalyst and <em>tert</em>-butyl hydroperoxide (TBHP) as the terminal oxidant. Comparing with known methods for the construction of <em>N</em>-benzylated sulfoximines, our protocol shows broad substrate scope with respect to both diarylmethanes and alkylarenes, and can be conducted in air with good functional group tolerance.</div></div>","PeriodicalId":96,"journal":{"name":"Organic & Biomolecular Chemistry","volume":"23 9","pages":"Pages 2111-2114"},"PeriodicalIF":2.7000,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Organic & Biomolecular Chemistry","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/org/science/article/pii/S1477052025000606","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
引用次数: 0

Abstract

A practical transition metal-free approach for the selective benzylation of NH-sulfoximines has been disclosed by using simple elemental iodine as the catalyst and tert-butyl hydroperoxide (TBHP) as the terminal oxidant. Comparing with known methods for the construction of N-benzylated sulfoximines, our protocol shows broad substrate scope with respect to both diarylmethanes and alkylarenes, and can be conducted in air with good functional group tolerance.

Abstract Image

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
i2催化nh -亚砜亚胺与二芳基甲烷和烷基烯的苄基化反应。
以单质碘为催化剂,过氧化叔丁基(TBHP)为末端氧化剂,提出了一种无过渡金属选择性苯基化nh -亚砜胺的方法。与已知的n -苄基化亚砜亚胺的构建方法相比,我们的方法对二芳基甲烷和烷基芳烃的底物范围都很广,并且可以在空气中进行,具有良好的官能团耐受性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Organic & Biomolecular Chemistry
Organic & Biomolecular Chemistry 化学-有机化学
CiteScore
5.50
自引率
9.40%
发文量
1056
审稿时长
1.3 months
期刊介绍: Organic & Biomolecular Chemistry is an international journal using integrated research in chemistry-organic chemistry. Founded in 2003 by the Royal Society of Chemistry, the journal is published in Semimonthly issues and has been indexed by SCIE, a leading international database. The journal focuses on the key research and cutting-edge progress in the field of chemistry-organic chemistry, publishes and reports the research results in this field in a timely manner, and is committed to becoming a window and platform for rapid academic exchanges among peers in this field. The journal's impact factor in 2023 is 2.9, and its CiteScore is 5.5.
期刊最新文献
Back cover Visible-light-induced oxidant-free thiol-disulfide transformation. Macrocyclic oxygen transfer in the conversion of fatty acid hydroperoxide to a single species of triol in physiological saline. Configurational stability of bis-ortho-methyl Tröger's base: methylene bridge substitution with retention of stereochemistry. Recursive anionic γ'-spiro-annulation of cyclic vinylogous esters with 2-vinylbenzoates.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1