Epstein-Barr virus-associated smooth muscle tumor with multiple lesions in a patient with AIDS.

IF 3.1 2区 医学 Q3 IMMUNOLOGY AIDS Pub Date : 2025-03-01 Epub Date: 2025-01-30 DOI:10.1097/QAD.0000000000004051
Xiu-Mei Zhen, Zhi-Hong Liu, Lu Zhang, Fang Xiao, Bo-Ming Liao
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Abstract

Epstein-Barr virus-associated smooth muscle tumors (EBV-SMTs) represent a rare category of soft tissue tumors that are predominantly seen in individuals with compromised immune systems. Pathologically, EBV-SMT has malignant potential because of its unpredictable nature. These tumors can manifest at various anatomical sites or even multiple lesions in different locations. Among the various forms of EBV-SMT, individuals with HIV infection or AIDS exhibit the poorest survival outcomes. The efficacy of antiretroviral therapy (ART), either as a standalone treatment or in combination with localized tumor interventions remains uncertain. The highlights of this article are the clinical diversity and various treatment possibilities for multisite AIDS-related EBV-SMT.

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爱泼斯坦-巴尔病毒相关的平滑肌肿瘤伴多处病变的艾滋病患者。
eb病毒相关的平滑肌肿瘤(ebv - smt)是一种罕见的软组织肿瘤,主要见于免疫系统受损的个体。病理上,EBV-SMT因其不可预测的性质而具有恶性潜能。这些肿瘤可以表现在不同的解剖部位,甚至不同部位的多个病变。在各种形式的EBV-SMT中,感染艾滋病毒或艾滋病的个体表现出最差的生存结果。抗逆转录病毒治疗(ART)的疗效,无论是单独治疗还是与局部肿瘤干预相结合,仍然不确定。本文的重点是多位点艾滋病相关EBV-SMT的临床多样性和各种治疗可能性。
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来源期刊
AIDS
AIDS 医学-病毒学
CiteScore
5.90
自引率
5.30%
发文量
478
审稿时长
3 months
期刊介绍: ​​​​​​​​​​​​​​​​​Publishing the very latest ground breaking research on HIV and AIDS. Read by all the top clinicians and researchers, AIDS has the highest impact of all AIDS-related journals. With 18 issues per year, AIDS guarantees the authoritative presentation of significant advances. The Editors, themselves noted international experts who know the demands of your work, are committed to making AIDS the most distinguished and innovative journal in the field. Submitted articles undergo a preliminary review by the editor. Some articles may be returned to authors without further consideration. Those being considered for publication will undergo further assessment and peer-review by the editors and those invited to do so from a reviewer pool.
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