Occupational Exposure to Air Pollutants and Higher Risk of COPD in Construction Workers: A Meta-Analysis Study.

Abstract

Introduction: Construction sites generate high levels of air pollution, contributing to more than 4% of particulate matter in the atmosphere. Literature indicates that on-site pollution is an important factor that contributes to lung impairments in construction workers. Chronic obstructive pulmonary disease (COPD) and acute respiratory distress syndrome (ADRS) are known to be exacerbated because of exposure to a variety of construction pollutants mainly particulate matter (PM10, PM2.5).

Methods: We conducted a systematic review and meta-analysis to assess whether exposure to construction site pollutants is associated with impairment of pulmonary parameters like Forced vital capacity (FVC), Forced expiration volume in 1 sec (FEV1) and FEV1/FVC. A total of 221 publications of observational studies were reviewed and 18 were selected; the data of which were meta-analyzed.

Results and discussion: In all studies the test subjects (construction workers) exposed to occupational air pollutants showed significantly lower FVC and FEV1 as compared expected levels (p≤ 0.01). The calculated Odds ratio indicates that there is positive association between COPD as compared to ARDS and exposure to pollutants.