A study to compare and correlate the effect of a yogic lifestyle on Framingham, Q RISK 3, and WHO risk scores among high-risk cardiovascular subjects.

Neha Saboo, Aayusheee Rao, Sudhanshu Kacker
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Abstract

Background: Cardiovascular diseases (CVDs) are a group of disorders of the heart and blood vessels. Yoga is a low-cost, easily accessible lifestyle modification program that holds as an approach to decreasing cardiometabolic risk factors and increasing exercise self-efficacy among high-risk subjects. This study aimed to assess the impact of the yogic lifestyle (including diet) on cardiovascular risk scores by using the Framingham (FRS), QRISK3 score, and World Health Organization (WHO) CVD risk prediction charts at baseline, three months, and six months. The present study compares and correlates FRS, QRISK3, and WHO cardiovascular risk scores.

Methodology: The experimental interventional study was conducted among the high-risk population at RUHS College of Medical Sciences and Associated Group of Hospitals, Jaipur. Framingham risk Score, QRISK3 score, and WHO CVD risk prediction charts were used as a method of measurement for the outcome of interest at baseline, three months, and six months in the study and control group. Randomization and allocation in yoga and control groups were performed using computer-generated random numbers. The statistical analysis was done using advanced SPSS-22 software at significant level tests as p≤0.05, ensuring the highest level of accuracy. Data were analyzed using a one-way variance ANOVA test analysis at baseline, three, and six months. Pearson correlation analysis was done to compare different risk scores.

Results: Participants had a mean age of 48.43 ± 6.4 years. Baseline values (mean±SD) of FRS, Qrisk3, WHO were 24.59±10.15,28.59±10.11,15.71±6.07. After six months of yogic lifestyle, these values decreased significantly to 15.1±7.05, 20.09±7.08, and 13.85±4.96. The decrease in cardiovascular scores was statistically significant (p<0.0001), providing strong evidence for the effectiveness of the yogic lifestyle. Pearson correlation analysis results depict that FRS and Q risk 3 (r=0.840, p<0.0001), FRS and WHO risk chart (r=0.768, p<0.0001), Q risk3 and WHO risk chart (r=0.778, p<0.0001) have a statistically significant strong positive correlation.

Conclusion: This study's findings suggest that a 24-week yogic lifestyle intervention (including diet) significantly decreased FRS, Q RISK 3, and WHO CVD risk scores among high-risk subjects compared to the control group.

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一项比较和关联瑜伽生活方式对高危心血管受试者Framingham、Q RISK 3和WHO风险评分影响的研究。
背景:心血管疾病(cvd)是一组心脏和血管疾病。瑜伽是一种低成本、容易获得的生活方式改变项目,是降低心脏代谢风险因素和提高高风险人群运动自我效能的一种方法。本研究旨在通过使用Framingham (FRS)、QRISK3评分和世界卫生组织(WHO) CVD风险预测图,在基线、3个月和6个月评估瑜伽生活方式(包括饮食)对心血管风险评分的影响。本研究比较并关联了FRS、QRISK3和WHO心血管风险评分。方法:在斋浦尔RUHS医学科学学院和联合医院集团的高危人群中进行实验性介入研究。使用Framingham风险评分、QRISK3评分和WHO心血管疾病风险预测图作为测量研究和对照组基线、3个月和6个月时感兴趣的结果的方法。瑜伽组和对照组采用计算机生成的随机数进行随机化和分配。采用先进的SPSS-22软件进行统计分析,p≤0.05为显著性水平检验,保证了最高水平的准确性。在基线、3个月和6个月时,数据采用单因素方差分析。采用Pearson相关分析比较不同风险评分。结果:患者平均年龄48.43±6.4岁。FRS、Qrisk3、WHO的基线值(平均±SD)分别为24.59±10.15、28.59±10.11、15.71±6.07。经过6个月的瑜伽生活方式后,这些数值显著下降到15.1±7.05,20.09±7.08和13.85±4.96。结论:本研究结果表明,与对照组相比,24周的瑜伽生活方式干预(包括饮食)可显著降低高危受试者的FRS、Q RISK 3和WHO CVD风险评分。
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