Profiles and Predictor of Pesticide and Metal Mixtures in Urine Among Solar Greenhouse Workers: Findings From the Measures of Environment and the Health Outcomes Study.

Siyuan Wang, Jianjian Su, Xin Song, Binshuo Hu, Yanan Pan, Xiaowen Ding, Xiaodong Liu, Chunguang Ding, Tian Chen, Xiaojun Zhu, Huadong Xu, Tenglong Yan
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Abstract

Objective: The aim of this study was to evaluate the exposure profiles and predictors for solar greenhouse workers to chemical mixtures.

Methods: Two hundred eighty-one solar greenhouse workers in China were included in this study. Six pesticides and 14 metals in urine were determined using chromatography-mass spectrometry. Pearson correlation, k-means clustering, and principal component analysis were used.

Results: The Pearson correlation coefficient showed that the correlation between similar chemicals was stronger than that between different types of chemicals. The k-means clustering showed that the female workers and multiple greenhouse workers had significantly higher chemical concentrations. The principal component analysis results showed that six principal components explain over 50% of the data variance, each dominated by specific chemicals.

Conclusion: This study provided important insights into the exposure characteristics and predictive factors of chemical mixtures among solar greenhouse workers.

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日光温室工人尿液中农药和金属混合物的概况和预测因素:来自环境测量和健康结果研究的结果。
目的:本研究的目的是评估日光温室工人对化学混合物的暴露概况和预测因素。方法:以全国2881名日光温室工作人员为研究对象。采用色谱-质谱联用法测定了尿液中的6种农药和14种金属。使用Pearson相关、k-means聚类和主成分分析。结果:Pearson相关系数显示,相似化学品之间的相关性强于不同类型化学品之间的相关性。k-means聚类结果表明,女性和多个温室工人的化学物质浓度显著高于其他温室工人。主成分分析结果表明,6个主成分解释了50%以上的数据方差,每个主成分都由特定的化学物质主导。结论:本研究对日光温室工人化学混合物的暴露特征及其预测因素有重要意义。
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