The Application of Benziodazole-Type O2NO-I(III) Compound as a Nitrating Reagent for Nitration of Phenols and Anilines.

IF 3.6 2区 化学 Q1 CHEMISTRY, ORGANIC Journal of Organic Chemistry Pub Date : 2025-02-14 Epub Date: 2025-01-31 DOI:10.1021/acs.joc.4c02738
Yuli Sun, Haofeng Shi, Jiaxin He, Kaiyue Yang, Dongxue Yin, Dan Xiao, Yunfei Du
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Abstract

A benziodazole-type O2NO-I(III) compound was used as a nitrating reagent to react with a series of electron-rich arenes including substituted phenols and anilines, affording the corresponding nitration products under mild conditions. Mechanistically, O2NO-I(III) compound generates the reactive nitrogen dioxide (NO2) species, which enables the nitration of phenols and anilines.

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苯并唑型O2NO-I(III)化合物在苯酚和苯胺硝化中的应用。
以一种苯并唑型O2NO-I(III)化合物为硝化试剂,与取代酚类、苯胺类等一系列富电子芳烃反应,在温和条件下生成相应的硝化产物。从机理上讲,O2NO-I(III)化合物产生活性二氧化氮(NO2),使苯酚和苯胺的硝化作用成为可能。
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来源期刊
Journal of Organic Chemistry
Journal of Organic Chemistry 化学-有机化学
CiteScore
6.20
自引率
11.10%
发文量
1467
审稿时长
2 months
期刊介绍: Journal of Organic Chemistry welcomes original contributions of fundamental research in all branches of the theory and practice of organic chemistry. In selecting manuscripts for publication, the editors place emphasis on the quality and novelty of the work, as well as the breadth of interest to the organic chemistry community.
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