Intracellular enhancement technique for gadoxetic acid-enhanced hepatobiliary-phase magnetic resonance imaging: evaluation of hepatic function

IF 2.3 3区医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Abdominal Radiology Pub Date : 2025-01-31 DOI:10.1007/s00261-025-04817-y

Dara Fonseca, Yuko Nakamura, Toru Higaki, Shogo Maeda, Takashi Nishihara, Yoshitaka Bito, Masahiro Takizawa, Shota Kondo, Ryo Higashino, Shintaro Morishita, Yuji Akiyama, Shingo Fukuma, Tomokazu Kawaoka, Masataka Tsuge, Shiro Oka, Kazuo Awai

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Abstract

Purpose

To investigate the utility of intracellular enhancement (ICE) technique which suppresses signals from the extracellular space for the evaluation of hepatic function on gadoxetic acid-enhanced hepatobiliary-phase (HBP) images.

Methods

We subjected 67 patients with suspected neoplastic hepatic lesions to gadoxetic acid-enhanced HBP imaging with and without ICE [i-HBP, conventional-HBP (c-HBP)]. A radiologist calculated the liver/spleen contrast (LSC) [LSC = signal intensity (SI) of liver/SI of spleen]. Receiver-operating analysis was used to evaluate the diagnostic value of the LSC on i-HBP- (i-LSC) and c-HBP images (c-LSC) to differentiate between Child-Pugh classes A and B.

Results

Of the 67 patients, 57 were in Child-Pugh class A and 10 were in class B. For their differentiation, the area under the curve value of i-LSC was higher than of c-LSC (0.81 vs. 0.68).

Conclusions

ICE technique can improve the accuracy of estimating hepatic function on HBP images.

Graphical abstract

Abstract Image

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肝胆道期磁共振成像细胞内增强技术：肝功能评价。

目的：探讨细胞内增强（ICE）技术抑制来自细胞外空间的信号在加多etic酸增强肝胆期（HBP）图像上评估肝功能的应用。方法：我们对67例疑似肝肿瘤性病变的患者进行加多辛酸增强HBP成像，有或没有ICE [i-HBP，常规HBP (c-HBP)]。放射科医师计算肝脏/脾脏对比（LSC） [LSC =肝脏信号强度(SI) /脾脏信号强度]。采用受体操作分析评价LSC在i-HBP- (i-LSC)和c-HBP （c-LSC）影像上对Child-Pugh A、b级鉴别的诊断价值。结果：67例患者中Child-Pugh A级57例，b级10例，其曲线下面积值高于c-LSC（0.81比0.68）。结论：ICE技术可提高HBP图像估计肝功能的准确性。

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来源期刊

Abdominal Radiology Medicine-Radiology, Nuclear Medicine and Imaging

CiteScore

5.20

自引率

8.30%

发文量

334

期刊介绍： Abdominal Radiology seeks to meet the professional needs of the abdominal radiologist by publishing clinically pertinent original, review and practice related articles on the gastrointestinal and genitourinary tracts and abdominal interventional and radiologic procedures. Case reports are generally not accepted unless they are the first report of a new disease or condition, or part of a special solicited section. Reasons to Publish Your Article in Abdominal Radiology: · Official journal of the Society of Abdominal Radiology (SAR) · Published in Cooperation with: European Society of Gastrointestinal and Abdominal Radiology (ESGAR) European Society of Urogenital Radiology (ESUR) Asian Society of Abdominal Radiology (ASAR) · Efficient handling and Expeditious review · Author feedback is provided in a mentoring style · Global readership · Readers can earn CME credits