Surgical treatment of epilepsy. Clinical aspects in children.

O Henriksen
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Abstract

Neurosurgery, mainly temporal lobectomy, has given substantial relief of serious seizure problems in two-thirds of children with intractable epilepsy. Since the prognoses of children with an intractable epilepsy is poor, surgery should be considered. To prevent sequela of a long standing seizure disorder and side effects of antiepileptic medication as well as the development of mirror foci, surgery should be considered at an early age. The age at which surgery should be undertaken depends upon several factors, for instance: the seizure problem, the EEG findings--are they persistently focal and do they fit with the seizures? Is there a malignant development of the epilepsy and little or no chance of remission? And especially, if there is brain pathology in concordance with the clinical findings and EEG signs, neurosurgery should not be postponed. It is of great advantage for children with an intractable epilepsy to be evaluated at an epilepsy center. Both the children and their parents will profit from the evaluation and information gained as well as education by a multiprofessional team. This will optimise the difficult decision process which may lead to neurosurgery.

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癫痫的外科治疗。儿童临床方面。
神经外科手术,主要是颞叶切除术,已经大大缓解了三分之二的难治性癫痫患儿的严重癫痫发作问题。由于顽固性癫痫患儿预后较差,应考虑手术治疗。为了防止长期发作障碍的后遗症和抗癫痫药物的副作用以及镜像病灶的发展,应在早期考虑手术。手术的年龄取决于几个因素,例如:癫痫问题,脑电图结果——它们是否持续集中,是否与癫痫发作相符?癫痫是否有恶性发展并且几乎没有缓解的机会?特别是,如果有脑部病理符合临床表现和脑电图征象,神经外科手术不应推迟。在癫痫中心对顽固性癫痫患儿进行评估是非常有利的。孩子和他们的父母都将受益于多专业团队的评估和获得的信息以及教育。这将优化可能导致神经外科手术的困难决策过程。
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Proceedings of the Annual Meeting of the Norwegian Neurological Association. November 2010. Oslo, Norway. Selected articles from the Annual Meeting of the Norwegian Neurological Association, November 2009, Oslo, Norway. Selected articles from the Annual Meeting of the Norwegian Neurological Association, 26-30 November 2007, Oslo, Norway. Advances in the pathophysiology of status epilepticus. Childhood convulsive status epilepticus: epidemiology, management and outcome.
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