Association Between Lung Ultrasound Score and PaO2/FiO2 Ratio in Neonatal Pneumonia: A Prospective Cohort Study

IF 1.4 4区医学 Q3 ACOUSTICS Journal of Clinical Ultrasound Pub Date : 2025-01-31 DOI:10.1002/jcu.23928

Manrong Liu, Jinling Mo, Changliang Nong, Lifeng Huang, Xiaoying Zhao, Mi Qin, Ke Ding

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Abstract

Objectives

Lung ultrasonography (LUS) is increasingly used to assess pulmonary diseases due to its safety and convenience. This study aimed to find out the association between the LUS score and the PaO₂/FiO₂ ratio in neonatal pneumonia.

Methods

This study prospectively enrolled 57 neonates with suspected pneumonia. LUS score (range 0–48) was evaluated by assessing 12 lung regions. The PaO₂/FiO₂ ratio was calculated by dividing the arterial oxygen partial pressure by the fraction of inspired oxygen from blood gas analysis. Correlations were analyzed using Pearson's correlation coefficient.

Results

Birth weight ranged 1 100–4 500 g (median 2 925 g), gestational age 27–41 weeks (median 37 weeks), and age 1–28 days (median 1 day). The LUS score was significantly correlated with the PaO₂/FiO₂ ratio (r = 0.758, p < 0.001), arterial oxygen partial pressure (r = 0.731, p < 0.001), partial pressure of carbon dioxide (r = 0.213, p < 0.001), and oxygen saturation (r = 0.196, p < 0.001).

Conclusions

Our study demonstrates significant correlations between the LUS score and blood gas analysis indices in neonatal pneumonia.

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新生儿肺炎肺超声评分与PaO2/FiO2比值的相关性：一项前瞻性队列研究

目的：肺超声检查（LUS）因其安全、方便而越来越多地用于肺部疾病的评估。本研究旨在探讨新生儿肺炎LUS评分与PaO2/FiO2比值的关系。方法：本研究前瞻性纳入57例疑似肺炎的新生儿。LUS评分（范围0-48）通过评估12个肺区域进行评估。PaO2/FiO2的比值是通过动脉氧分压除以血气分析中吸入氧的分数来计算的。使用Pearson相关系数分析相关性。结果：出生体重1 100 ~ 4 500 g（中位2 925 g），胎龄27 ~ 41周（中位37周），胎龄1 ~ 28天（中位1天）。新生儿肺炎LUS评分与PaO2/FiO2比值显著相关（r = 0.758, p）。结论：本研究显示新生儿肺炎LUS评分与血气分析指标存在显著相关性。

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来源期刊

Journal of Clinical Ultrasound 医学-核医学

CiteScore

1.90

自引率

0.00%

发文量

248

审稿时长

6 months

期刊介绍： The Journal of Clinical Ultrasound (JCU) is an international journal dedicated to the worldwide dissemination of scientific information on diagnostic and therapeutic applications of medical sonography. The scope of the journal includes--but is not limited to--the following areas: sonography of the gastrointestinal tract, genitourinary tract, vascular system, nervous system, head and neck, chest, breast, musculoskeletal system, and other superficial structures; Doppler applications; obstetric and pediatric applications; and interventional sonography. Studies comparing sonography with other imaging modalities are encouraged, as are studies evaluating the economic impact of sonography. Also within the journal''s scope are innovations and improvements in instrumentation and examination techniques and the use of contrast agents. JCU publishes original research articles, case reports, pictorial essays, technical notes, and letters to the editor. The journal is also dedicated to being an educational resource for its readers, through the publication of review articles and various scientific contributions from members of the editorial board and other world-renowned experts in sonography.