Improving cardiometabolic risk factors in Aboriginal and Torres Strait Islander people in northeast Arnhem Land: single arm trial of a co-designed dietary and lifestyle program

IF 8.5 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Medical Journal of Australia Pub Date : 2025-01-30 DOI:10.5694/mja2.52593
Hasthi UW Dissanayake, George Gurruwiwi, J Dhurrkay, Josh C Tynan, Sabine Braat, Benjamin Harrap, Tim Trudgen, Sarah Hanieh, Bronwyn Clark, Michaela Spencer, Michael Christie, Emma Tonkin, Emily Armstrong, Leonard C Harrison, John M Wentworth, Julie K Brimblecombe, Beverley-Ann Biggs
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Abstract

Objective

To evaluate the impact of a 4-month dietary and lifestyle program co-designed and led by Aboriginal and Torres Strait Islander people on weight and metabolic markers, diet, and physical activity in overweight and obese adults in a remote Indigenous community.

Study design

Single arm, pre–post intervention study.

Setting, participants

Adult residents (18–65 years) of a remote Northern Territory community with body mass index (BMI) values of at least 25 kg/m2 or waist circumferences exceeding 94 cm (men) or 80 cm (women).

Intervention

Hope for Health, a culturally sensitive 4-month program supporting self-managed health improvement based on dietary and lifestyle change, 1 August to 30 November 2022.

Main outcome measures

Weight loss of at least 5%; changes in BMI, waist circumference, other metabolic markers (blood pressure, biomarkers of metabolic health and inflammation), diet, and physical activity; participant perceptions of the program.

Results

We assessed outcomes for 55 participants who completed weight assessments at both baseline and program end (mean age, 42.5 years [standard deviation, 10.1 years]; 36 women [65%]). Forty participants lost and 15 gained weight; overall mean weight loss was 1.5 kg (95% confidence interval [CI], 0.5–2.4 kg), and ten participants (18%; 95% CI, 9–31%) achieved at least 5% weight reduction. The mean change in BMI (53 participants) was –0.60 kg/m2 (95% CI, –0.93 to –0.27 kg/m2), in waist circumference (53 participants) –3.2 cm (95% CI, –4.7 to –1.7 cm), and in low-density lipoprotein cholesterol level (37 participants) –0.28 mmol/L (95% CI, –0.47 to –0.08 mmol/L); the relative decline in the HbA1c level geometric mean (50 participants) was 11% (95% CI, 6–15%). The intake of breads and cereals (median change, –1.5 [95% CI, –2.0 to –1.0] serves/day) and sugar-sweetened beverages (–0.6 [95% CI, –1.4 to –0.1] serves/day) declined; the amount of moderate and vigorous physical activity increased by a median of 103 min/day (95% CI, 74–136 min/day; 19 participants). The program focus on integrating healthy bodies and networks of kin, healthy governance, vibrant language and ceremony, and a healthy environment were seen as central to its value and benefit.

Conclusions

Community appreciation of the program and the improvements in cardiometabolic risk factors are encouraging, providing an example of a culturally sensitive, co-designed initiative led by Indigenous people for reducing the prevalence of chronic disease in remote areas.

Trial registration

Australian New Zealand Clinical Trials Registry (ACTRN12622000174785; prospective: 2 February 2022).

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改善阿纳姆地东北部土著人和托雷斯海峡岛民的心脏代谢危险因素:共同设计的饮食和生活方式项目的单臂试验
目的:评估由土著和托雷斯海峡岛民共同设计和领导的为期4个月的饮食和生活方式计划对偏远土著社区超重和肥胖成年人的体重和代谢指标、饮食和身体活动的影响。研究设计:单组,干预前后研究。背景,参与者:来自北领地偏远社区的成年居民(18-65岁),身体质量指数(BMI)值至少为25kg /m2或腰围超过94 cm(男性)或80 cm(女性)。干预措施:2022年8月1日至11月30日实施的“健康希望”,这是一个对文化敏感的4个月方案,支持通过改变饮食和生活方式自我管理改善健康。主要结局指标:体重减轻至少5%;BMI、腰围、其他代谢指标(血压、代谢健康和炎症的生物标志物)、饮食和身体活动的变化;参与者对项目的看法。结果:我们评估了55名在基线和项目结束时完成体重评估的参与者的结果(平均年龄42.5岁[标准差10.1岁];36名女性[65%])。40名参与者体重减轻,15名体重增加;总体平均体重减轻1.5 kg(95%置信区间[CI], 0.5-2.4 kg), 10名参与者(18%;95% CI, 9-31%)达到了至少5%的体重减轻。BMI(53名参与者)平均变化为-0.60 kg/m2 (95% CI, -0.93至-0.27 kg/m2),腰围(53名参与者)平均变化为-3.2 cm (95% CI, -4.7至-1.7 cm),低密度脂蛋白胆固醇水平(37名参与者)平均变化为-0.28 mmol/L (95% CI, -0.47至-0.08 mmol/L);HbA1c水平几何平均值(50名参与者)的相对下降为11% (95% CI, 6-15%)。面包和谷物(变化中值为-1.5 [95% CI, -2.0至-1.0]份/天)和含糖饮料(-0.6 [95% CI, -1.4至-0.1]份/天)的摄入量下降;中等和剧烈体力活动的量中位数增加了103分钟/天(95% CI, 74-136分钟/天);19个参与者)。该方案的重点是整合健康的身体和亲属网络、健康的治理、充满活力的语言和仪式,以及健康的环境,这被视为其价值和利益的核心。结论:社区对该计划的赞赏和心脏代谢风险因素的改善令人鼓舞,提供了一个由土著人民领导的文化敏感、共同设计的倡议,以减少偏远地区慢性病的流行。试验注册:澳大利亚新西兰临床试验注册中心(ACTRN12622000174785;预计时间:2022年2月2日)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Medical Journal of Australia
Medical Journal of Australia 医学-医学:内科
CiteScore
9.40
自引率
5.30%
发文量
410
审稿时长
3-8 weeks
期刊介绍: The Medical Journal of Australia (MJA) stands as Australia's foremost general medical journal, leading the dissemination of high-quality research and commentary to shape health policy and influence medical practices within the country. Under the leadership of Professor Virginia Barbour, the expert editorial team at MJA is dedicated to providing authors with a constructive and collaborative peer-review and publication process. Established in 1914, the MJA has evolved into a modern journal that upholds its founding values, maintaining a commitment to supporting the medical profession by delivering high-quality and pertinent information essential to medical practice.
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