Women who experience heavy menstrual bleeding: prevalence and characteristics from young adulthood to midlife, Australia, 2000–2021: a longitudinal cohort survey study

IF 6.8 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Medical Journal of Australia Pub Date : 2025-01-30 DOI:10.5694/mja2.52596
Louise Wilson, Tessa Copp, Martha Hickey, Bec Jenkinson, Susan J Jordan, Rachel Thompson, Gita D Mishra, Jenny A Doust
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Abstract

Objectives

To estimate the prevalence of heavy menstrual bleeding among Australian women from young adulthood to midlife (22–48 years) and investigate the characteristics of women who experience this condition; to investigate the relationship of heavy menstrual bleeding and health-related quality of life.

Study design

Longitudinal cohort survey study (Australian Longitudinal Study on Women's Health, ALSWH).

Setting, participants

Australia; baseline cohort of 14 247 women born during 1973–1978, recruited in 1996; eight post-baseline surveys undertaken at 3-year intervals, 2000–2021.

Main outcome measures

Self-reported frequency of heavy menstrual bleeding during the preceding twelve months (never/rarely, sometimes, often); frequency of heavy menstrual bleeding by socio-demographic, behavioural, health, and reproduction-related characteristics; mean physical and mental health-related quality of life scores (36-item Short Form health survey, SF-36) by frequency of heavy menstrual bleeding. Results are weighted to adjust for oversampling of participants from rural and remote areas.

Results

Data for 11 311 respondents to at least one ALSWH post-baseline survey were included in our prevalence analysis. The prevalence of sometimes or often experiencing heavy menstrual bleeding increased from 17.6% at age 22 years (124 of 691 respondents) to 32.1% at 48 years (359 of 1132 respondents); the proportion who reported often experiencing the condition increased from 6.1% (45 participants) to 12.1% (136 participants). The likelihood of often experiencing heavy menstrual bleeding increased with body mass index (40 kg/m2 or greater v 18.5–24.9 kg/m2: risk ratio [RR], 2.27; 95% confidence interval [CI], 1.93–2.67), and was greater for respondents who reported low iron levels (RR, 2.26; 95% CI, 2.03–2.51) or endometriosis (RR, 2.29; 95% CI, 2.06–2.54). Similar associations were seen for sometimes experiencing heavy bleeding. Mean health-related quality of life scores for women who reported heavy menstrual bleeding were lower in all domains and for the summary mental health and physical health scores than for women who reported never or rarely experiencing the condition; the differences were greater for women who often experienced heavy menstrual bleeding.

Conclusions

Heavy menstrual bleeding was reported by large minorities of women of reproductive age, and the proportion increased with age. Many women experience symptoms that have a substantial impact on their physical and mental health-related quality of life.

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经历大量月经出血的女性:从青年到中年的患病率和特征,澳大利亚,2000-2021:一项纵向队列调查研究
目的:估计澳大利亚女性从青年到中年(22-48岁)大量月经出血的患病率,并调查经历这种情况的女性的特征;探讨月经大出血与健康相关生活质量的关系。研究设计:纵向队列调查研究(澳大利亚妇女健康纵向研究,ALSWH)。地点、参与者:澳大利亚;基线队列为14247名1973-1978年出生的妇女,于1996年招募;2000-2021年,每3年进行8次基线后调查。主要结局指标:自我报告的前12个月月经大出血频率(从不/很少,有时,经常);按社会人口、行为、健康和生殖相关特征划分的月经大出血频率;生理和心理健康相关生活质量评分(36项简短健康调查,SF-36)按月经大出血频率。对结果进行加权,以调整来自农村和偏远地区的参与者的过采样。结果:11 311名至少参加一次ALSWH基线后调查的受访者的数据被纳入我们的患病率分析。有时或经常经历大量月经出血的患病率从22岁时的17.6%(691名应答者中的124名)增加到48岁时的32.1%(1132名应答者中的359名);报告经常经历这种情况的比例从6.1%(45名参与者)增加到12.1%(136名参与者)。经常出现大量月经出血的可能性随着体重指数(40 kg/m2或更高)的增加而增加。18.5-24.9 kg/m2:风险比[RR], 2.27;95%可信区间[CI], 1.93-2.67),并且对于报告铁水平较低的受访者(RR, 2.26;95% CI, 2.03-2.51)或子宫内膜异位症(RR, 2.29;95% ci, 2.06-2.54)。有时出现大出血也有类似的关联。报告月经大量出血的妇女在所有领域的平均健康相关生活质量得分以及总结的心理健康和身体健康得分均低于报告从未或很少出现月经大量出血的妇女;对于经常经历大量月经出血的女性来说,这种差异更大。结论:少数育龄妇女月经大出血发生率高,且随年龄增长比例增加。许多妇女所经历的症状对其身心健康相关的生活质量产生重大影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Medical Journal of Australia
Medical Journal of Australia 医学-医学:内科
CiteScore
9.40
自引率
5.30%
发文量
410
审稿时长
3-8 weeks
期刊介绍: The Medical Journal of Australia (MJA) stands as Australia's foremost general medical journal, leading the dissemination of high-quality research and commentary to shape health policy and influence medical practices within the country. Under the leadership of Professor Virginia Barbour, the expert editorial team at MJA is dedicated to providing authors with a constructive and collaborative peer-review and publication process. Established in 1914, the MJA has evolved into a modern journal that upholds its founding values, maintaining a commitment to supporting the medical profession by delivering high-quality and pertinent information essential to medical practice.
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