Exploring hypertension-linked diseases: a comprehensive review of innovative drug combinations with enhanced therapeutic potential.

IF 3.1 4区 医学 Q2 PHARMACOLOGY & PHARMACY Naunyn-Schmiedeberg's archives of pharmacology Pub Date : 2025-06-01 Epub Date: 2025-01-31 DOI:10.1007/s00210-025-03819-3
Bhavesh Thakkar, Hetvi Dadhaniya, Kiran Dudhat
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Abstract

Hypertension, a prevalent cardiovascular condition affecting a substantial portion of the global population, remains a formidable health challenge associated with a multitude of complications. This review article provides a comprehensive examination of hypertension, its various complications, and the emergence of a novel management technique that shows promising potential in transforming the therapeutic landscape. Over the years, conventional treatment approaches, encompassing lifestyle modifications, dietary interventions, and pharmacotherapy, have been the mainstay in managing hypertension. However, these strategies fall short in achieving optimal blood pressure control and preventing complications in a significant number of patients. Consequently, the medical community has ventured into exploring innovative management techniques to tackle this unmet medical need. The focal point of this review centers on the emergence of a new management technique for hypertension that exhibits promise in preclinical and clinical studies. The latest research findings shed light on the efficacy and safety of this innovative approach, which encompasses pharmaceutical agents, medical devices, and non-invasive interventions. Through critical analysis and discussion, we explore the potential impact of these novel strategies on hypertension management and patient outcomes. In conclusion, this review article provides a comprehensive overview of hypertension, its complications, and the promising emergence of innovative management techniques. By acknowledging the complexity of hypertension and the potential of new therapeutic avenues, we aspire to pave the way for improved patient care, enhanced quality of life, and ultimately, the mitigation of hypertension-related morbidity and mortality.

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探索高血压相关疾病:具有增强治疗潜力的创新药物组合的综合综述
高血压是一种影响全球相当一部分人口的普遍心血管疾病,它仍然是一项与多种并发症相关的巨大健康挑战。这篇综述文章提供了一个全面的检查高血压,它的各种并发症,并出现了一种新的管理技术,显示有希望改变治疗前景。多年来,包括生活方式改变、饮食干预和药物治疗在内的传统治疗方法一直是控制高血压的主要方法。然而,这些策略在实现最佳血压控制和预防大量患者并发症方面存在不足。因此,医学界已经冒险探索创新的管理技术,以解决这一未满足的医疗需求。这篇综述的焦点集中在一种新的高血压管理技术的出现,在临床前和临床研究中显示出希望。最新的研究结果阐明了这种创新方法的有效性和安全性,其中包括药物制剂、医疗器械和非侵入性干预措施。通过批判性的分析和讨论,我们探讨了这些新策略对高血压管理和患者预后的潜在影响。总之,这篇综述文章提供了一个全面的概述高血压,其并发症,并有希望的创新管理技术的出现。通过认识到高血压的复杂性和新的治疗途径的潜力,我们渴望为改善患者护理,提高生活质量,并最终减轻高血压相关的发病率和死亡率铺平道路。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
6.20
自引率
5.60%
发文量
142
审稿时长
4-8 weeks
期刊介绍: Naunyn-Schmiedeberg''s Archives of Pharmacology was founded in 1873 by B. Naunyn, O. Schmiedeberg and E. Klebs as Archiv für experimentelle Pathologie und Pharmakologie, is the offical journal of the German Society of Experimental and Clinical Pharmacology and Toxicology (Deutsche Gesellschaft für experimentelle und klinische Pharmakologie und Toxikologie, DGPT) and the Sphingolipid Club. The journal publishes invited reviews, original articles, short communications and meeting reports and appears monthly. Naunyn-Schmiedeberg''s Archives of Pharmacology welcomes manuscripts for consideration of publication that report new and significant information on drug action and toxicity of chemical compounds. Thus, its scope covers all fields of experimental and clinical pharmacology as well as toxicology and includes studies in the fields of neuropharmacology and cardiovascular pharmacology as well as those describing drug actions at the cellular, biochemical and molecular levels. Moreover, submission of clinical trials with healthy volunteers or patients is encouraged. Short communications provide a means for rapid publication of significant findings of current interest that represent a conceptual advance in the field.
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