Primary extraskeletal osteosarcoma of rectal mesentery: a rare case and literature review.

IF 2.5 3区医学 Q3 ONCOLOGY World Journal of Surgical Oncology Pub Date : 2025-01-29 DOI:10.1186/s12957-025-03676-7

Zhikui Huo, Yao Sun, Jinghui Chang, Guo-Dong Li, Jian Shi, Cheng Quan, Li-Na Zhang, Ting-Ting Yang, Feng-Jia Shang, Yong-Ping Yang

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Abstract

Background: Extraskeletal osteosarcoma (ESOS) is a rare kind of sarcoma with a low preoperative diagnosis and a poor prognosis. ESOS arising from abdominal mesentery is extremely rare. Increasing diagnostic methods and standardizing treatment protocols are crucial issues of ESOS.

Case presentation: We report the case of a 52-year-old female ESOS patient. She had a history of ovarian carcinoma (stage IIIC) surgery two years before, with five cycles of chemotherapy. A mass was found during postoperative examinations. A R0 surgical resection was performed. Post-operational pathological report plus intra-surgery findings supported a diagnosis of ESOS. She is still alive 10 months post-operationally, with routine blood and radiographical examinations.

Conclusion: Enhancing awareness of this extremely rare disease together with advancements in diagnostic methods will hopefully enable earlier recognition and initiation of treatment. Protocols for standardizing treatments require a larger multi-center collaboration and more data analysis.

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直肠肠系膜原发性骨外骨肉瘤一例罕见并文献复习。

背景：骨外骨肉瘤（ESOS）是一种罕见的肉瘤，术前诊断低，预后差。由腹部肠系膜引起的ESOS极为罕见。增加诊断方法和规范治疗方案是ESOS的关键问题。病例介绍：我们报告一例52岁女性ESOS患者。2年前有卵巢癌（IIIC期）手术史，化疗5个周期。术后检查发现肿块。R0手术切除。术后病理报告及术中表现均支持ESOS的诊断。术后10个月，患者仍存活，进行了常规血液和x线检查。结论：提高对这种极其罕见的疾病的认识以及诊断方法的进步有望使早期发现和开始治疗。标准化治疗方案需要更大的多中心合作和更多的数据分析。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

World Journal of Surgical Oncology ONCOLOGY-SURGERY

CiteScore

4.70

自引率

15.60%

发文量

362

审稿时长

3 months

期刊介绍： World Journal of Surgical Oncology publishes articles related to surgical oncology and its allied subjects, such as epidemiology, cancer research, biomarkers, prevention, pathology, radiology, cancer treatment, clinical trials, multimodality treatment and molecular biology. Emphasis is placed on original research articles. The journal also publishes significant clinical case reports, as well as balanced and timely reviews on selected topics. Oncology is a multidisciplinary super-speciality of which surgical oncology forms an integral component, especially with solid tumors. Surgical oncologists around the world are involved in research extending from detecting the mechanisms underlying the causation of cancer, to its treatment and prevention. The role of a surgical oncologist extends across the whole continuum of care. With continued developments in diagnosis and treatment, the role of a surgical oncologist is ever-changing. Hence, World Journal of Surgical Oncology aims to keep readers abreast with latest developments that will ultimately influence the work of surgical oncologists.